Intuniv and Sedation - a phase IV clinical study of FDA data

Summary:

Sedation is reported as a side effect among people who take Intuniv (guanfacine hydrochloride), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Vyvanse, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Sedation when taking Intuniv. It is created by eHealthMe based on reports of 3,469 people who have side effects when taking Intuniv from the FDA, and is updated regularly.

What is Intuniv?

Intuniv has active ingredients of guanfacine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 3,959 Intuniv users. Check the latest studies of Intuniv.

What is Sedation?

Sedation is found to be associated with 1,318 drugs and 1,289 conditions by eHealthMe. Check the latest studies of Sedation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

3,469 people reported to have side effects when taking Intuniv.
Among them, 35 people (1.01%) have Sedation.

Among these 35 people:

How long have people been on Intuniv when they have Sedation? *

What is the gender of people who have Sedation when taking Intuniv? *

female: 24.14 %
male: 75.86 %

What is the age of people who have Sedation when taking Intuniv? *

What are other drugs people take besides Intuniv? *

What are other side effects people have besides Sedation? *

Fatigue (feeling of tiredness): 9 people, 25.71%
Dizziness: 9 people, 25.71%
Bradycardia (abnormally slow heart action): 4 people, 11.43%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 11.43%
Gynecomastia (enlargement of the gland tissue of the male breast): 3 people, 8.57%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 8.57%
Hypotension (abnormally low blood pressure): 3 people, 8.57%
Head Injury: 3 people, 8.57%
Fall: 3 people, 8.57%
Suicidal Ideation: 3 people, 8.57%

What are the existing conditions these people have? *

Oppositional Defiant Disorder (a childhood disorder described by the diagnostic and statistical manual of mental disorders): 2 people, 5.71%
Anger: 2 people, 5.71%
Asthma: 2 people, 5.71%
Stress And Anxiety: 2 people, 5.71%
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups): 1 person, 2.86%
Depression: 1 person, 2.86%
Affective Disorder (mental disorder): 1 person, 2.86%
Aggression: 1 person, 2.86%
Agitation (state of anxiety or nervous excitement): 1 person, 2.86%
Allergic Rhinitis: 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Intuniv and have Sedation?

- Check whether Sedation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Intuniv:

Intuniv (3,959 reports)

Sedation treatments and more:

Sedation (52,223 reports)

Browse all side effects of Intuniv:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sedation:

Sedation (1,318 drugs)

Browse all the conditions that are associated with Sedation:

Sedation (1,289 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on guanfacine hydrochloride (the active ingredients of Intuniv) and Intuniv (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.