Invirase and Hepatic failure - a phase IV clinical study of FDA data

Summary:

Hepatic failure is reported as a side effect among people who take Invirase (saquinavir mesylate), especially for people who are male, 30-39 old, have been taking the drug for 1 - 6 months also take Zerit, and have Hiv infection.

The phase IV clinical study analyzes which people have Hepatic failure when taking Invirase. It is created by eHealthMe based on reports of 2,682 people who have side effects when taking Invirase from the FDA, and is updated regularly.

What is Invirase?

Invirase has active ingredients of saquinavir mesylate. eHealthMe is studying from 2,690 Invirase users. Check the latest studies of Invirase.

What is Hepatic failure?

Hepatic failure (liver failure) is found to be associated with 1,540 drugs and 1,892 conditions by eHealthMe. Check the latest studies of Hepatic failure.

On Jul, 17, 2026

2,682 people reported to have side effects when taking Invirase.
Among them, 46 people (1.72%) have Hepatic failure.

Among these 46 people:

How long have people been on Invirase when they have Hepatic failure? *

What is the gender of people who have Hepatic failure when taking Invirase? *

female: 13.33 %
male: 86.67 %

What is the age of people who have Hepatic failure when taking Invirase? *

What are other drugs people take besides Invirase? *

What are other side effects people have besides Hepatic failure? *

Fever: 12 people, 26.09%
Ascites (accumulation of fluid in the abdominal cavity): 11 people, 23.91%
Blood Bilirubin Increased: 10 people, 21.74%
Liver Function Tests Nos Abnormal: 9 people, 19.57%
Lactic Acidosis (low ph in body tissues): 8 people, 17.39%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 17.39%
Cough: 7 people, 15.22%
Hepatomegaly (abnormal enlargement of the liver): 7 people, 15.22%
Blood Amylase Increased: 7 people, 15.22%
Nausea (feeling of having an urge to vomit): 7 people, 15.22%

What are the existing conditions these people have? *

Hiv Infection: 11 people, 23.91%
Cd4 Lymphocytes Decreased: 2 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Invirase and have Hepatic failure?

- Check whether Hepatic failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Invirase:

Invirase (2,690 reports)

Hepatic failure treatments and more:

Hepatic failure (44,058 reports)

Browse all side effects of Invirase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic failure:

Hepatic failure (1,540 drugs)

Browse all the conditions that are associated with Hepatic failure:

Hepatic failure (1,892 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on saquinavir mesylate (the active ingredients of Invirase) and Invirase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.