Invokana and Joint injury - a phase IV clinical study of FDA data

Summary:

Joint injury is reported as a side effect among people who take Invokana (canagliflozin), especially for people who are male, 50-59 old, have been taking the drug for 1 - 2 years also take Metformin, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Joint injury when taking Invokana. It is created by eHealthMe based on reports of 29,682 people who have side effects when taking Invokana from the FDA, and is updated regularly.

What is Invokana?

Invokana has active ingredients of canagliflozin. It is often used in diabetes. eHealthMe is studying from 29,937 Invokana users. Check the latest studies of Invokana.

What is Joint injury?

Joint injury is found to be associated with 1,233 drugs and 1,133 conditions by eHealthMe. Check the latest studies of Joint injury.

On Jul, 09, 2026

29,682 people reported to have side effects when taking Invokana.
Among them, 17 people (0.06%) have Joint injury.

Among these 17 people:

How long have people been on Invokana when they have Joint injury? *

What is the gender of people who have Joint injury when taking Invokana? *

female: 35.71 %
male: 64.29 %

What is the age of people who have Joint injury when taking Invokana? *

What are other drugs people take besides Invokana? *

What are other side effects people have besides Joint injury? *

Fall: 10 people, 58.82%
Limb Injury: 7 people, 41.18%
Gait Disturbance: 6 people, 35.29%
Mobility Decreased (ability to move is reduced): 5 people, 29.41%
Weight Decreased: 4 people, 23.53%
Joint Swelling: 4 people, 23.53%
Joint Pain: 4 people, 23.53%
Memory Loss: 3 people, 17.65%
Muscle Aches (muscle pain): 3 people, 17.65%
Constipation: 3 people, 17.65%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 17.65%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 17.65%
Weight Loss: 2 people, 11.76%
Blood Glucose Increased: 2 people, 11.76%
Gout (uric acid crystals building up in the body): 1 person, 5.88%
Asthma: 1 person, 5.88%
Blood Glucose Abnormal: 1 person, 5.88%
Gait Disturbance: 1 person, 5.88%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Invokana and have Joint injury?

- Check whether Joint injury is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Invokana:

Invokana (29,937 reports)

Joint injury treatments and more:

Joint injury (28,959 reports)

Browse all side effects of Invokana:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint injury:

Joint injury (1,233 drugs)

Browse all the conditions that are associated with Joint injury:

Joint injury (1,133 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on canagliflozin (the active ingredients of Invokana) and Invokana (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.