Irinotecan hydrochloride and Hypoaesthesia - a phase IV clinical study of FDA data

Summary:

Hypoaesthesia is reported as a side effect among people who take Irinotecan hydrochloride (irinotecan hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Avastin, and have Abdominal distension.

The phase IV clinical study analyzes which people have Hypoaesthesia when taking Irinotecan hydrochloride. It is created by eHealthMe based on reports of 7,131 people who have side effects when taking Irinotecan hydrochloride from the FDA, and is updated regularly.

What is Irinotecan hydrochloride?

Irinotecan hydrochloride has active ingredients of irinotecan hydrochloride. It is often used in cancer. eHealthMe is studying from 7,166 Irinotecan hydrochloride users. Check the latest studies of Irinotecan hydrochloride.

What is Hypoaesthesia?

Hypoaesthesia (reduced sense of touch or sensation) is found to be associated with 2,888 drugs and 3,185 conditions by eHealthMe. Check the latest studies of Hypoaesthesia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

7,131 people reported to have side effects when taking Irinotecan hydrochloride.
Among them, 62 people (0.87%) have Hypoaesthesia.

Could Irinotecan hydrochloride cause Hypoaesthesia?

Among these 62 people:

How long have people been on Irinotecan hydrochloride when they have Hypoaesthesia? *

What is the gender of people who have Hypoaesthesia when taking Irinotecan hydrochloride? *

female: 53.7 %
male: 46.3 %

What is the age of people who have Hypoaesthesia when taking Irinotecan hydrochloride? *

What are other drugs people take besides Irinotecan hydrochloride? *

What are other side effects people have besides Hypoaesthesia? *

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 19 people, 30.65%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 17 people, 27.42%
Dyspnea (difficult or laboured breathing): 17 people, 27.42%
Abdominal Pain: 16 people, 25.81%
Rhinorrhea (watery mucus discharge from the nose): 15 people, 24.19%
Weakness: 15 people, 24.19%
Pain: 15 people, 24.19%
Malaise (a feeling of general discomfort or uneasiness): 14 people, 22.58%
Nausea (feeling of having an urge to vomit): 13 people, 20.97%
Hypotension (abnormally low blood pressure): 12 people, 19.35%

What are the existing conditions these people have? *

Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 12 people, 19.35%
Pancreatic Neuroendocrine Tumor: 12 people, 19.35%
Abdominal Pain: 12 people, 19.35%
Abdominal Distension: 12 people, 19.35%
Iron Deficiency: 11 people, 17.74%
Oesophageal Carcinoma (cancer tumour of oesophagus): 10 people, 16.13%
Colon Cancer: 10 people, 16.13%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 9 people, 14.52%
High Blood Pressure: 3 people, 4.84%
Pancreatic Carcinoma (pancreatic cancer): 3 people, 4.84%

* Approximation only. Some reports may have incomplete information.

Do you take Irinotecan hydrochloride and have Hypoaesthesia?

- Check whether Hypoaesthesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Irinotecan hydrochloride:

Irinotecan hydrochloride (7,166 reports)

Hypoaesthesia treatments and more:

Hypoaesthesia (189,312 reports)

Browse all side effects of Irinotecan hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoaesthesia:

Hypoaesthesia (2,888 drugs)

Browse all the conditions that are associated with Hypoaesthesia:

Hypoaesthesia (3,185 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on irinotecan hydrochloride (the active ingredients of Irinotecan hydrochloride) and Irinotecan hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.