Isoptin and Hypoglycemia - a phase IV clinical study of FDA data

Summary:

Hypoglycemia is reported as a side effect among people who take Isoptin (verapamil hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Humalog, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Hypoglycemia when taking Isoptin. It is created by eHealthMe based on reports of 5,465 people who have side effects when taking Isoptin from the FDA, and is updated regularly.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

What is Hypoglycemia?

Hypoglycemia (low blood sugar) is found to be associated with 1,702 drugs and 2,379 conditions by eHealthMe. Check the latest studies of Hypoglycemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 06, 2026

5,465 people reported to have side effects when taking Isoptin.
Among them, 46 people (0.84%) have Hypoglycemia.

Among these 46 people:

How long have people been on Isoptin when they have Hypoglycemia? *

What is the gender of people who have Hypoglycemia when taking Isoptin? *

female: 56.1 %
male: 43.9 %

What is the age of people who have Hypoglycemia when taking Isoptin? *

What are other drugs people take besides Isoptin? *

What are other side effects people have besides Hypoglycemia? *

Fall: 7 people, 15.22%
Hypotension (abnormally low blood pressure): 6 people, 13.04%
Acute Kidney Failure: 5 people, 10.87%
Anaemia Macrocytic (a macrocytic class of anaemia): 4 people, 8.70%
Vitamin B12 Deficiency: 4 people, 8.70%
Lactic Acidosis (low ph in body tissues): 4 people, 8.70%
Overdose: 4 people, 8.70%
Hyperglycemia (high blood sugar): 3 people, 6.52%
Bradycardia (abnormally slow heart action): 3 people, 6.52%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 6.52%

What are the existing conditions these people have? *

Type 2 Diabetes: 11 people, 23.91%
Diabetes: 6 people, 13.04%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 8.70%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 4 people, 8.70%
Type 1 Diabetes: 4 people, 8.70%
High Blood Cholesterol: 2 people, 4.35%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 2 people, 4.35%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 4.35%
Osteoporosis (bones weak and more likely to break): 2 people, 4.35%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Isoptin and have Hypoglycemia?

- Check whether Hypoglycemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoptin:

Isoptin (5,539 reports)

Hypoglycemia treatments and more:

Hypoglycemia (57,734 reports)

Browse all side effects of Isoptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoglycemia:

Hypoglycemia (1,702 drugs)

Browse all the conditions that are associated with Hypoglycemia:

Hypoglycemia (2,379 conditions)

Related publications that referenced our studies

Hipoglisemi RB, "Rasagiline-Induced Hypoglycemia", , 2016 Jan .
Hipoglisemi RB, "Rasagiline-Induced Hypoglycemia", , 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride (the active ingredients of Isoptin) and Isoptin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.