Isoptin and Shock - a phase IV clinical study of FDA data

Summary:

Shock is reported as a side effect among people who take Isoptin (verapamil hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Agranulocytosis.

The phase IV clinical study analyzes which people have Shock when taking Isoptin. It is created by eHealthMe based on reports of 5,465 people who have side effects when taking Isoptin from the FDA, and is updated regularly.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

What is Shock?

Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin) is found to be associated with 1,217 drugs and 1,753 conditions by eHealthMe. Check the latest studies of Shock.

On Jul, 16, 2026

5,465 people reported to have side effects when taking Isoptin.
Among them, 78 people (1.43%) have Shock.

Among these 78 people:

How long have people been on Isoptin when they have Shock? *

What is the gender of people who have Shock when taking Isoptin? *

female: 73.61 %
male: 26.39 %

What is the age of people who have Shock when taking Isoptin? *

What are other drugs people take besides Isoptin? *

Lasix: 16 people, 20.51%
Zofran: 11 people, 14.10%
Vancomycin: 11 people, 14.10%
Diflucan: 11 people, 14.10%
Neupogen: 11 people, 14.10%
Imodium: 11 people, 14.10%
Claforan: 10 people, 12.82%
Amoxicillin And Clavulanate Potassium: 8 people, 10.26%
Heparin: 6 people, 7.69%
Demerol: 6 people, 7.69%

What are other side effects people have besides Shock? *

Acute Kidney Failure: 19 people, 24.36%
Hypotension (abnormally low blood pressure): 18 people, 23.08%
Fever: 14 people, 17.95%
Erythema Multiforme (a type of hypersensitivity reaction): 14 people, 17.95%
Hyperkalemia (damage to or disease of the kidney): 13 people, 16.67%
Itching: 12 people, 15.38%
Bradycardia (abnormally slow heart action): 12 people, 15.38%
Circulatory Collapse: 11 people, 14.10%
Drug Toxicity: 10 people, 12.82%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 9 people, 11.54%

What are the existing conditions these people have? *

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 11 people, 14.10%
Agitation (state of anxiety or nervous excitement): 6 people, 7.69%
Suicide Attempt: 6 people, 7.69%
Constipation: 5 people, 6.41%
Nausea (feeling of having an urge to vomit): 4 people, 5.13%
Arrhythmias (irregular heartbeat): 4 people, 5.13%
Burkitt's Lymphoma (cancer of the lymphatic system): 4 people, 5.13%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 5.13%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 4 people, 5.13%
Itching: 4 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Isoptin and have Shock?

- Check whether Shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoptin:

Isoptin (5,539 reports)

Shock treatments and more:

Shock (28,534 reports)

Browse all side effects of Isoptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shock:

Shock (1,217 drugs)

Browse all the conditions that are associated with Shock:

Shock (1,753 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride (the active ingredients of Isoptin) and Isoptin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.