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Isordil and Arthritis - a phase IV clinical study of FDA data

Summary:

Arthritis is reported as a side effect among people who take Isordil (isosorbide dinitrate), especially for people who are female, 60+ old, also take Lasix, and have Pain.

The phase IV clinical study analyzes which people have Arthritis when taking Isordil. It is created by eHealthMe based on reports of 2,999 people who have side effects when taking Isordil from the FDA, and is updated regularly.

What is Isordil?

Isordil has active ingredients of isosorbide dinitrate. eHealthMe is studying from 3,022 Isordil users. Check the latest studies of Isordil.

What is Arthritis?

Arthritis (form of joint disorder that involves inflammation of one or more joints) is found to be associated with 1,962 drugs and 2,259 conditions by eHealthMe. Check the latest studies of Arthritis.

On Jul, 28, 2026

2,999 people reported to have side effects when taking Isordil.
Among them, 21 people (0.7%) have Arthritis.

Could Isordil cause Arthritis?

Among these 21 people:

What is the gender of people who have Arthritis when taking Isordil? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Arthritis when taking Isordil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 12.5 %
  • 60+: 87.5 %

What are other drugs people take besides Isordil? *

  1. Lasix: 13 people, 61.90%
  2. Coreg: 10 people, 47.62%
  3. Aspirin: 9 people, 42.86%
  4. Coumadin: 9 people, 42.86%
  5. Lisinopril: 7 people, 33.33%
  6. Norvasc: 7 people, 33.33%
  7. Unasyn: 6 people, 28.57%
  8. Lopressor: 6 people, 28.57%
  9. Keflex: 6 people, 28.57%
  10. Protonix: 6 people, 28.57%

What are other side effects people have besides Arthritis? *

  1. Joint Pain: 12 people, 57.14%
  2. Rashes (redness): 10 people, 47.62%
  3. Oedema Peripheral (superficial swelling): 10 people, 47.62%
  4. Skin Discoloration: 9 people, 42.86%
  5. High Blood Pressure: 9 people, 42.86%
  6. Pain: 9 people, 42.86%
  7. Skin Ulcer: 8 people, 38.10%
  8. Back Pain: 7 people, 33.33%
  9. Cardiac Failure Congestive: 7 people, 33.33%
  10. Acute Kidney Failure: 7 people, 33.33%

What are the existing conditions these people have? *

  1. Pain: 7 people, 33.33%
  2. High Blood Pressure: 4 people, 19.05%
  3. Cardiac Failure Congestive: 3 people, 14.29%
  4. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.52%
  5. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 9.52%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 9.52%
  7. Type 2 Diabetes: 1 person, 4.76%
  8. Cardiac Failure: 1 person, 4.76%
  9. Chest Pain: 1 person, 4.76%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Isordil and have Arthritis?

- Check whether Arthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isordil:

Arthritis treatments and more:

How severe was Arthritis and when was it recovered:

Expand to all the drugs that have ingredients of isosorbide dinitrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isordil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arthritis:

Browse all the conditions that are associated with Arthritis:

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate (the active ingredients of Isordil) and Isordil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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