Isordil and Peripheral neuropathy - a phase IV clinical study of FDA data

Summary:

Peripheral neuropathy is reported as a side effect among people who take Isordil (isosorbide dinitrate), especially for people who are female, 60+ old, also take Pravachol, and have Asthma.

The phase IV clinical study analyzes which people have Peripheral neuropathy when taking Isordil. It is created by eHealthMe based on reports of 2,999 people who have side effects when taking Isordil from the FDA, and is updated regularly.

What is Isordil?

Isordil has active ingredients of isosorbide dinitrate. eHealthMe is studying from 3,022 Isordil users. Check the latest studies of Isordil.

What is Peripheral neuropathy?

Peripheral neuropathy (damage to nerves of the peripheral nervous system) is found to be associated with 503 drugs and 879 conditions by eHealthMe. Check the latest studies of Peripheral neuropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

2,999 people reported to have side effects when taking Isordil.
Among them, 17 people (0.57%) have Peripheral neuropathy.

Could Isordil cause Peripheral neuropathy?

Among these 17 people:

What is the gender of people who have Peripheral neuropathy when taking Isordil? *

female: 64.71 %
male: 35.29 %

What is the age of people who have Peripheral neuropathy when taking Isordil? *

What are other drugs people take besides Isordil? *

What are other side effects people have besides Peripheral neuropathy? *

Weakness: 5 people, 29.41%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 29.41%
Chest Pain: 4 people, 23.53%
Nausea (feeling of having an urge to vomit): 4 people, 23.53%
Difficulty In Walking: 4 people, 23.53%
Aspartate Aminotransferase Increased: 3 people, 17.65%
Heart Attack: 2 people, 11.76%
Dehydration (dryness resulting from the removal of water): 2 people, 11.76%
Cardiac Failure Congestive: 2 people, 11.76%
Cellulitis (infection under the skin): 2 people, 11.76%

What are the existing conditions these people have? *

High Blood Cholesterol: 1 person, 5.88%
Asthma: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Isordil and have Peripheral neuropathy?

- Check whether Peripheral neuropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isordil:

Isordil (3,022 reports)

Browse all side effects of Isordil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral neuropathy:

Peripheral neuropathy (503 drugs)

Browse all the conditions that are associated with Peripheral neuropathy:

Peripheral neuropathy (879 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate (the active ingredients of Isordil) and Isordil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.