Isosorbide dinitrate and Mastication disorder - a phase IV clinical study of FDA data

Summary:

Mastication disorder is reported as a side effect among people who take Isosorbide dinitrate (isosorbide dinitrate), especially for people who are male, 60+ old, also take Neurontin, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Mastication disorder when taking Isosorbide dinitrate. It is created by eHealthMe based on reports of 13,073 people who have side effects when taking Isosorbide dinitrate from the FDA, and is updated regularly.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

What is Mastication disorder?

Mastication disorder (disease of chewing food) is found to be associated with 714 drugs and 547 conditions by eHealthMe. Check the latest studies of Mastication disorder.



On Jul, 26, 2026

13,073 people reported to have side effects when taking Isosorbide dinitrate.
Among them, 13 people (0.1%) have Mastication disorder.

Could Isosorbide dinitrate cause Mastication disorder?

Among these 13 people:

What is the gender of people who have Mastication disorder when taking Isosorbide dinitrate? *

  • female: 7.69 %
  • male: 92.31 %

What is the age of people who have Mastication disorder when taking Isosorbide dinitrate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Isosorbide dinitrate? *

  1. Zolpidem: 13 people, 100.00%
  2. Flexeril: 13 people, 100.00%
  3. Oxycontin: 13 people, 100.00%
  4. Zometa: 13 people, 100.00%
  5. Neurontin: 13 people, 100.00%
  6. Levaquin: 12 people, 92.31%
  7. Mirapex: 12 people, 92.31%
  8. Celexa: 12 people, 92.31%
  9. Furosemide: 12 people, 92.31%
  10. Nitroglycerin: 12 people, 92.31%

What are other side effects people have besides Mastication disorder? *

  1. Anaemia (lack of blood): 13 people, 100.00%
  2. Stress And Anxiety: 13 people, 100.00%
  3. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 13 people, 100.00%
  4. Multiple Myeloma (cancer of the plasma cells): 13 people, 100.00%
  5. Neuropathy Peripheral (surface nerve damage): 13 people, 100.00%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 13 people, 100.00%
  7. Osteonecrosis Of Jaw (death of bone of jaw): 13 people, 100.00%
  8. Pain: 13 people, 100.00%
  9. Dyspnea (difficult or laboured breathing): 13 people, 100.00%
  10. Pneumonia: 13 people, 100.00%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 13 people, 100.00%
  2. Bone Disorder: 1 person, 7.69%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide dinitrate and have Mastication disorder?

- Check whether Mastication disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isosorbide dinitrate:

Mastication disorder treatments and more:

How severe was Mastication disorder and when was it recovered:

Expand to all the drugs that have ingredients of isosorbide dinitrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isosorbide dinitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mastication disorder:

Browse all the conditions that are associated with Mastication disorder:


How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate (the active ingredients of Isosorbide dinitrate) and Isosorbide dinitrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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