Isosorbide dinitrate and Pseudomembranous colitis - a phase IV clinical study of FDA data

Summary:

Pseudomembranous colitis is reported as a side effect among people who take Isosorbide dinitrate (isosorbide dinitrate), especially for people who are male, 60+ old, also take Primidone, and have Mantle cell lymphoma.

The phase IV clinical study analyzes which people have Pseudomembranous colitis when taking Isosorbide dinitrate. It is created by eHealthMe based on reports of 13,073 people who have side effects when taking Isosorbide dinitrate from the FDA, and is updated regularly.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

What is Pseudomembranous colitis?

Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon) is found to be associated with 428 drugs and 934 conditions by eHealthMe. Check the latest studies of Pseudomembranous colitis.

On Jul, 14, 2026

13,073 people reported to have side effects when taking Isosorbide dinitrate.
Among them, 21 people (0.16%) have Pseudomembranous colitis.

Could Isosorbide dinitrate cause Pseudomembranous colitis?

Among these 21 people:

What is the gender of people who have Pseudomembranous colitis when taking Isosorbide dinitrate? *

female: 47.62 %
male: 52.38 %

What is the age of people who have Pseudomembranous colitis when taking Isosorbide dinitrate? *

What are other drugs people take besides Isosorbide dinitrate? *

What are other side effects people have besides Pseudomembranous colitis? *

Diarrhea: 9 people, 42.86%
Liver Disorder (liver diseases): 6 people, 28.57%
Hepatitis B: 6 people, 28.57%
Lymphocyte Count Decreased: 5 people, 23.81%
Hypokalemia (low potassium): 4 people, 19.05%
Collapse (sudden functional breakdown): 4 people, 19.05%
White Blood Cell Count Decreased: 4 people, 19.05%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 3 people, 14.29%
Thrombocytopenia (decrease of platelets in blood): 3 people, 14.29%
Haemoglobin Decreased: 3 people, 14.29%

What are the existing conditions these people have? *

Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 6 people, 28.57%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 14.29%
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 2 people, 9.52%
Osteoporosis (bones weak and more likely to break): 2 people, 9.52%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 9.52%
Helicobacter Pylori Infection (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium): 2 people, 9.52%
Diabetes: 2 people, 9.52%
Cystinosis (abnormal accumulation of the amino acid cystine): 2 people, 9.52%
Chronic Kidney Disease: 2 people, 9.52%
Thyroid Diseases: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide dinitrate and have Pseudomembranous colitis?

- Check whether Pseudomembranous colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isosorbide dinitrate:

Isosorbide dinitrate (13,180 reports)

Browse all side effects of Isosorbide dinitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pseudomembranous colitis:

Pseudomembranous colitis (428 drugs)

Browse all the conditions that are associated with Pseudomembranous colitis:

Pseudomembranous colitis (934 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate (the active ingredients of Isosorbide dinitrate) and Isosorbide dinitrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.