Isosorbide mononitrate and Bone marrow depression - a phase IV clinical study of FDA data

Summary:

Bone marrow depression is reported as a side effect among people who take Isosorbide mononitrate (isosorbide mononitrate), especially for people who are male, 60+ old, also take Amlodipine Besylate, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Bone marrow depression when taking Isosorbide mononitrate. It is created by eHealthMe based on reports of 26,444 people who have side effects when taking Isosorbide mononitrate from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Bone marrow depression?

Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells) is found to be associated with 350 drugs and 465 conditions by eHealthMe. Check the latest studies of Bone marrow depression.

On Jul, 26, 2026

26,444 people reported to have side effects when taking Isosorbide mononitrate.
Among them, 14 people (0.05%) have Bone marrow depression.

Could Isosorbide mononitrate cause Bone marrow depression?

Among these 14 people:

What is the gender of people who have Bone marrow depression when taking Isosorbide mononitrate? *

female: 14.29 %
male: 85.71 %

What is the age of people who have Bone marrow depression when taking Isosorbide mononitrate? *

What are other drugs people take besides Isosorbide mononitrate? *

What are other side effects people have besides Bone marrow depression? *

Thrombocytopenia (decrease of platelets in blood): 5 people, 35.71%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 21.43%
Pneumonia: 3 people, 21.43%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 14.29%
Anaemia (lack of blood): 2 people, 14.29%
Aplastic Anemia: 2 people, 14.29%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 14.29%
Red Cell Aplasia (a type of anaemia affecting the precursors to red blood cells): 2 people, 14.29%
Coughing Up Blood: 2 people, 14.29%
Septic Shock (shock due to blood infection): 2 people, 14.29%

What are the existing conditions these people have? *

Chronic Renal Failure (kidney failure): 2 people, 14.29%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 14.29%
Pneumonia: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide mononitrate and have Bone marrow depression?

- Check whether Bone marrow depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isosorbide mononitrate:

Isosorbide mononitrate (26,858 reports)

Browse all side effects of Isosorbide mononitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone marrow depression:

Bone marrow depression (350 drugs)

Browse all the conditions that are associated with Bone marrow depression:

Bone marrow depression (465 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate (the active ingredients of Isosorbide mononitrate) and Isosorbide mononitrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.