Isosorbide mononitrate and Face oedema - a phase IV clinical study of FDA data

Summary:

Face oedema is reported as a side effect among people who take Isosorbide mononitrate (isosorbide mononitrate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Furosemide, and have Hyperphosphataemia.

The phase IV clinical study analyzes which people have Face oedema when taking Isosorbide mononitrate. It is created by eHealthMe based on reports of 26,444 people who have side effects when taking Isosorbide mononitrate from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Face oedema?

Face oedema (swelling of face) is found to be associated with 1,322 drugs and 2,110 conditions by eHealthMe. Check the latest studies of Face oedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

26,444 people reported to have side effects when taking Isosorbide mononitrate.
Among them, 37 people (0.14%) have Face oedema.

Could Isosorbide mononitrate cause Face oedema?

Among these 37 people:

How long have people been on Isosorbide mononitrate when they have Face oedema? *

What is the gender of people who have Face oedema when taking Isosorbide mononitrate? *

female: 25.71 %
male: 74.29 %

What is the age of people who have Face oedema when taking Isosorbide mononitrate? *

What are other drugs people take besides Isosorbide mononitrate? *

Famotidine: 8 people, 21.62%
Furosemide: 8 people, 21.62%
Diltiazem Hydrochloride: 5 people, 13.51%
Renagel: 5 people, 13.51%
Losartan Potassium: 4 people, 10.81%
Calcitriol: 4 people, 10.81%
Celebrex: 4 people, 10.81%
Simvastatin: 4 people, 10.81%
Carvedilol: 4 people, 10.81%
Allopurinol: 3 people, 8.11%

What are other side effects people have besides Face oedema? *

Dermatitis Exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss): 5 people, 13.51%
Rashes (redness): 4 people, 10.81%
Oedema Peripheral (superficial swelling): 4 people, 10.81%
Chest Pain: 4 people, 10.81%
Generalised Erythema (redness of the skin all over the body): 4 people, 10.81%
Cardiac Failure Chronic: 3 people, 8.11%
Fall: 3 people, 8.11%
Consciousness - Decreased: 3 people, 8.11%
Fever: 3 people, 8.11%
Cardiac Failure Congestive: 3 people, 8.11%

What are the existing conditions these people have? *

Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 4 people, 10.81%
Abdominal Discomfort: 3 people, 8.11%
Hyperhomocysteinaemia (abnormally high level of homocysteine in the blood): 3 people, 8.11%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 8.11%
Blood Uric Acid Increased: 3 people, 8.11%
Gastric Disorder (disease of stomach): 3 people, 8.11%
Heart Disease: 3 people, 8.11%
Cardiac Ventricular Disorder (ventricular dysfunction of heart): 3 people, 8.11%
Liver Disorder (liver diseases): 3 people, 8.11%
Urination - Excessive Volume: 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide mononitrate and have Face oedema?

- Check whether Face oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isosorbide mononitrate:

Isosorbide mononitrate (26,858 reports)

Face oedema treatments and more:

Face oedema (29,111 reports)

Browse all side effects of Isosorbide mononitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Face oedema:

Face oedema (1,322 drugs)

Browse all the conditions that are associated with Face oedema:

Face oedema (2,110 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate (the active ingredients of Isosorbide mononitrate) and Isosorbide mononitrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.