Isosorbide mononitrate and Feeling cold - a phase IV clinical study of FDA data

Summary:

Feeling cold is reported as a side effect among people who take Isosorbide mononitrate (isosorbide mononitrate), especially for people who are male, 60+ old, also take Plavix, and have Depression.

The phase IV clinical study analyzes which people have Feeling cold when taking Isosorbide mononitrate. It is created by eHealthMe based on reports of 26,444 people who have side effects when taking Isosorbide mononitrate from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Feeling cold?

Feeling cold is found to be associated with 1,338 drugs and 1,618 conditions by eHealthMe. Check the latest studies of Feeling cold.



On Jul, 06, 2026

26,444 people reported to have side effects when taking Isosorbide mononitrate.
Among them, 33 people (0.12%) have Feeling cold.

Could Isosorbide mononitrate cause Feeling cold?

Among these 33 people:

What is the gender of people who have Feeling cold when taking Isosorbide mononitrate? *

  • female: 43.75 %
  • male: 56.25 %

What is the age of people who have Feeling cold when taking Isosorbide mononitrate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 4.35 %
  • 50-59: 0.0 %
  • 60+: 95.65 %

What are other drugs people take besides Isosorbide mononitrate? *

  1. Plavix: 6 people, 18.18%
  2. Hydrochlorothiazide: 5 people, 15.15%
  3. Simvastatin: 4 people, 12.12%
  4. Aspirin: 4 people, 12.12%
  5. Candesartan Cilexetil: 4 people, 12.12%
  6. Norvasc: 4 people, 12.12%
  7. Singulair: 4 people, 12.12%
  8. Symbicort: 3 people, 9.09%
  9. Zanaflex: 3 people, 9.09%
  10. Lipitor: 3 people, 9.09%

What are other side effects people have besides Feeling cold? *

  1. Headache (pain in head): 9 people, 27.27%
  2. Malaise (a feeling of general discomfort or uneasiness): 8 people, 24.24%
  3. Fatigue (feeling of tiredness): 7 people, 21.21%
  4. Depression: 7 people, 21.21%
  5. Chest Pain: 6 people, 18.18%
  6. Weakness: 6 people, 18.18%
  7. Dyspnea (difficult or laboured breathing): 6 people, 18.18%
  8. Muscle Aches (muscle pain): 5 people, 15.15%
  9. Dizziness: 5 people, 15.15%
  10. Nasopharyngitis (inflammation of the nasopharynx): 5 people, 15.15%

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.12%
  2. Cardiac Disorder: 4 people, 12.12%
  3. Depression: 4 people, 12.12%
  4. Immunodeficiency Common Variable: 3 people, 9.09%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 9.09%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 9.09%
  7. Stress And Anxiety: 3 people, 9.09%
  8. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 6.06%
  9. Primary Immunodeficiency Syndrome: 2 people, 6.06%
  10. Pain: 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide mononitrate and have Feeling cold?

- Check whether Feeling cold is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isosorbide mononitrate:

Feeling cold treatments and more:

How severe was Feeling cold and when was it recovered:

Expand to all the drugs that have ingredients of isosorbide mononitrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isosorbide mononitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Feeling cold:

Browse all the conditions that are associated with Feeling cold:


How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate (the active ingredients of Isosorbide mononitrate) and Isosorbide mononitrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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