Isosorbide mononitrate and Sinus rhythm - a phase IV clinical study of FDA data

Summary:

Sinus rhythm is reported as a side effect among people who take Isosorbide mononitrate (isosorbide mononitrate), especially for people who are male, 60+ old, also take Amlodipine, and have Acute myocardial infarction.

The phase IV clinical study analyzes which people have Sinus rhythm when taking Isosorbide mononitrate. It is created by eHealthMe based on reports of 26,444 people who have side effects when taking Isosorbide mononitrate from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Sinus rhythm?

Sinus rhythm (normal beating of the heart) is found to be associated with 120 drugs and 120 conditions by eHealthMe. Check the latest studies of Sinus rhythm.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

26,444 people reported to have side effects when taking Isosorbide mononitrate.
Among them, 14 people (0.05%) have Sinus rhythm.

Could Isosorbide mononitrate cause Sinus rhythm?

Among these 14 people:

What is the gender of people who have Sinus rhythm when taking Isosorbide mononitrate? *

female: 14.29 %
male: 85.71 %

What is the age of people who have Sinus rhythm when taking Isosorbide mononitrate? *

What are other drugs people take besides Isosorbide mononitrate? *

What are other side effects people have besides Sinus rhythm? *

Cardiogenic Shock (inadequate circulation of blood): 13 people, 92.86%
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 10 people, 71.43%
Blood Creatinine Increased: 10 people, 71.43%
Hypotension (abnormally low blood pressure): 10 people, 71.43%
Blood Lactic Acid Abnormal: 8 people, 57.14%
Anuria (failure of the kidneys to produce urine): 8 people, 57.14%
Blood Pressure Abnormal: 8 people, 57.14%
Ph Body Fluid Abnormal: 6 people, 42.86%
Distributive Shock (hock caused by poor distribution of the blood flow): 6 people, 42.86%
Heart Rate Irregular: 6 people, 42.86%

What are the existing conditions these people have? *

Acute Myocardial Infarction (acute heart attack): 12 people, 85.71%
Hypotension (abnormally low blood pressure): 2 people, 14.29%
Dyspnea (difficult or laboured breathing): 2 people, 14.29%
Asthma: 2 people, 14.29%
Cardiogenic Shock (inadequate circulation of blood): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide mononitrate and have Sinus rhythm?

- Check whether Sinus rhythm is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isosorbide mononitrate:

Isosorbide mononitrate (26,858 reports)

Sinus rhythm treatments and more:

Sinus rhythm (678 reports)

Browse all side effects of Isosorbide mononitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus rhythm:

Sinus rhythm (120 drugs)

Browse all the conditions that are associated with Sinus rhythm:

Sinus rhythm (120 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate (the active ingredients of Isosorbide mononitrate) and Isosorbide mononitrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.