Jadenu and Dehydration - a phase IV clinical study of FDA data
Summary:
Dehydration is reported as a side effect among people who take Jadenu (deferasirox), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Jakafi, and have Iron overload.
The phase IV clinical study analyzes which people have Dehydration when taking Jadenu. It is created by eHealthMe based on reports of 4,173 people who have side effects when taking Jadenu from the FDA, and is updated regularly.
What is Jadenu?
Jadenu has active ingredients of deferasirox. eHealthMe is studying from 4,176 Jadenu users. Check the latest studies of Jadenu.
What is Dehydration?
Dehydration (dryness resulting from the removal of water) is found to be associated with 2,752 drugs and 3,350 conditions by eHealthMe. Check the latest studies of Dehydration.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
4,173 people reported to have side effects when taking Jadenu.
Among them, 50 people (1.2%) have Dehydration.

Among these 50 people:
How long have people been on Jadenu when they have Dehydration? *
- < 1 month: 50.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 25.0 %
- 1 - 2 years: 12.5 %
- 2 - 5 years: 12.5 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Dehydration when taking Jadenu? *
- female: 56.52 %
- male: 43.48 %
What is the age of people who have Dehydration when taking Jadenu? *
- 0-1: 0.0 %
- 2-9: 2.78 %
- 10-19: 5.56 %
- 20-29: 5.56 %
- 30-39: 19.44 %
- 40-49: 5.56 %
- 50-59: 2.78 %
- 60+: 58.33 %
What are other drugs people take besides Jadenu? *
- Jakafi: 10 people, 20.00%
- Magnesium: 9 people, 18.00%
- Vitamin B12: 9 people, 18.00%
- Oxbryta: 8 people, 16.00%
- Lasix: 7 people, 14.00%
- Exjade: 7 people, 14.00%
- Ditropan: 6 people, 12.00%
- Celexa: 6 people, 12.00%
- Vitamin D: 5 people, 10.00%
- Tylenol: 4 people, 8.00%
What are other side effects people have besides Dehydration? *
- Diarrhea: 24 people, 48.00%
- Fatigue (feeling of tiredness): 17 people, 34.00%
- Haemoglobin Decreased: 13 people, 26.00%
- Abdominal Pain Upper: 13 people, 26.00%
- Weight Decreased: 11 people, 22.00%
- Nausea (feeling of having an urge to vomit): 11 people, 22.00%
- Urinary Tract Infection: 11 people, 22.00%
- Fever: 10 people, 20.00%
- Red Blood Cell Count Decreased: 10 people, 20.00%
- Gait Disturbance: 9 people, 18.00%
What are the existing conditions these people have? *
- Iron Overload: 14 people, 28.00%
- Urinary Tract Infection: 10 people, 20.00%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 9 people, 18.00%
- Primary Myelofibrosis (primary disorder of the bone marrow): 7 people, 14.00%
- Brain Neoplasm (tumour of brain): 6 people, 12.00%
- Colitis (inflammation of colon): 6 people, 12.00%
- Pain: 3 people, 6.00%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 6.00%
- Iron Binding Capacity Total Abnormal: 3 people, 6.00%
- Haemosiderosis (general increase in tissue iron stores without associated tissue damage): 3 people, 6.00%
* Approximation only. Some reports may have incomplete information.
Do you take Jadenu and have Dehydration?
- Check whether Dehydration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Jadenu:
- Jadenu (4,176 reports)
Dehydration treatments and more:
- Dehydration (173,274 reports)
How severe was Dehydration and when was it recovered:
Expand to all the drugs that have ingredients of deferasirox:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Jadenu:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Dehydration:
- Dehydration (2,752 drugs)
Browse all the conditions that are associated with Dehydration:
- Dehydration (3,350 conditions)
Related publications that referenced our studies
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on deferasirox (the active ingredients of Jadenu) and Jadenu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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