Jadenu and Hearing loss - a phase IV clinical study of FDA data
Summary:
Hearing loss is reported as a side effect among people who take Jadenu (deferasirox), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Metformin, and have High blood pressure.
The phase IV clinical study analyzes which people have Hearing loss when taking Jadenu. It is created by eHealthMe based on reports of 4,173 people who have side effects when taking Jadenu from the FDA, and is updated regularly.
What is Jadenu?
Jadenu has active ingredients of deferasirox. eHealthMe is studying from 4,176 Jadenu users. Check the latest studies of Jadenu.
What is Hearing loss?
Hearing loss is found to be associated with 1,355 drugs and 2,378 conditions by eHealthMe. Check the latest studies of Hearing loss.
4,173 people reported to have side effects when taking Jadenu.
Among them, 30 people (0.72%) have Hearing loss.

Among these 30 people:
How long have people been on Jadenu when they have Hearing loss? *
- < 1 month: 50 %
- 1 - 6 months: 50 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hearing loss when taking Jadenu? *
- female: 27.27 %
- male: 72.73 %
What is the age of people who have Hearing loss when taking Jadenu? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 7.69 %
- 20-29: 0.0 %
- 30-39: 7.69 %
- 40-49: 7.69 %
- 50-59: 7.69 %
- 60+: 69.23 %
What are other drugs people take besides Jadenu? *
- Metformin: 6 people, 20.00%
- Exjade: 2 people, 6.67%
- Triamcinolone: 1 person, 3.33%
- Promacta: 1 person, 3.33%
- Oxbryta: 1 person, 3.33%
- Metformin Hydrochloride: 1 person, 3.33%
- Jardiance: 1 person, 3.33%
- Gleevec: 1 person, 3.33%
- Folic Acid: 1 person, 3.33%
- Fluoxetine: 1 person, 3.33%
What are other side effects people have besides Hearing loss? *
- Blood Iron Increased: 8 people, 26.67%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 7 people, 23.33%
- Diarrhea: 7 people, 23.33%
- Abdominal Pain Upper: 6 people, 20.00%
- Anorectal Discomfort: 6 people, 20.00%
- Feeling Abnormal: 4 people, 13.33%
- White Blood Cell Count Decreased: 4 people, 13.33%
- Haemoglobin Decreased: 4 people, 13.33%
- Thrombocytopenia (decrease of platelets in blood): 4 people, 13.33%
- Hypoacusis (loss of hearing): 3 people, 10.00%
What are the existing conditions these people have? *
- High Blood Pressure: 7 people, 23.33%
- Iron Overload: 6 people, 20.00%
- Thyroid Diseases: 4 people, 13.33%
- Diabetes: 3 people, 10.00%
- Haemochromatosis (body to absorb more iron than usual from food): 2 people, 6.67%
- Stasis Dermatitis (skin inflammation caused by blood pooling in the veins in your legs): 1 person, 3.33%
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 1 person, 3.33%
- Enlarged Prostate: 1 person, 3.33%
- Depression: 1 person, 3.33%
- Chronic Lymphocytic Leukaemia Recurrent (repeated cancer of blood cells known as lymphocytes): 1 person, 3.33%
* Approximation only. Some reports may have incomplete information.
Do you take Jadenu and have Hearing loss?
- Check whether Hearing loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Jadenu:
- Jadenu (4,176 reports)
Hearing loss treatments and more:
- Hearing loss (30,352 reports)
How severe was Hearing loss and when was it recovered:
Expand to all the drugs that have ingredients of deferasirox:
- Hearing loss and drugs with ingredients of deferasirox (204 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Jadenu:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hearing loss:
- Hearing loss (1,355 drugs)
Browse all the conditions that are associated with Hearing loss:
- Hearing loss (2,378 conditions)
Related publications that referenced our studies
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on deferasirox (the active ingredients of Jadenu) and Jadenu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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