Janumet and Poor quality sleep - a phase IV clinical study of FDA data

Summary:

Poor quality sleep is reported as a side effect among people who take Janumet (metformin hydrochloride; sitagliptin phosphate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zocor, and have High blood pressure.

The phase IV clinical study analyzes which people have Poor quality sleep when taking Janumet. It is created by eHealthMe based on reports of 24,406 people who have side effects when taking Janumet from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Poor quality sleep?

Poor quality sleep is found to be associated with 1,257 drugs and 1,167 conditions by eHealthMe. Check the latest studies of Poor quality sleep.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

24,406 people reported to have side effects when taking Janumet.
Among them, 41 people (0.17%) have Poor quality sleep.

Among these 41 people:

How long have people been on Janumet when they have Poor quality sleep? *

What is the gender of people who have Poor quality sleep when taking Janumet? *

female: 55.26 %
male: 44.74 %

What is the age of people who have Poor quality sleep when taking Janumet? *

What are other drugs people take besides Janumet? *

What are other side effects people have besides Poor quality sleep? *

Fatigue (feeling of tiredness): 12 people, 29.27%
Diarrhea: 9 people, 21.95%
Weakness: 7 people, 17.07%
Itching: 6 people, 14.63%
Dizziness: 6 people, 14.63%
Abdominal Discomfort: 6 people, 14.63%
Back Pain: 6 people, 14.63%
Cough: 5 people, 12.20%
Chest Pain: 5 people, 12.20%
Fall: 5 people, 12.20%

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 19.51%
High Blood Cholesterol: 5 people, 12.20%
Paranasal Sinus Hypersecretion: 4 people, 9.76%
Depression: 4 people, 9.76%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 9.76%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 9.76%
Pain: 3 people, 7.32%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 3 people, 7.32%
Delusion (a false belief or opinion): 2 people, 4.88%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 4.88%

* Approximation only. Some reports may have incomplete information.

Do you take Janumet and have Poor quality sleep?

- Check whether Poor quality sleep is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Janumet:

Janumet (25,023 reports)

Poor quality sleep treatments and more:

Poor quality sleep (25,207 reports)

How severe was Poor quality sleep and when was it recovered:

Poor quality sleep in Janumet

Expand to all the drugs that have ingredients of metformin hydrochloride; sitagliptin phosphate:

Poor quality sleep and drugs with ingredients of metformin hydrochloride; sitagliptin phosphate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Janumet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Poor quality sleep:

Poor quality sleep (1,257 drugs)

Browse all the conditions that are associated with Poor quality sleep:

Poor quality sleep (1,167 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride; sitagliptin phosphate (the active ingredients of Janumet) and Janumet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.