Janumet and Status epilepticus - a phase IV clinical study of FDA data

Summary:

Status epilepticus is reported as a side effect among people who take Janumet (metformin hydrochloride; sitagliptin phosphate), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Eliquis, and have Gout.

The phase IV clinical study analyzes which people have Status epilepticus when taking Janumet. It is created by eHealthMe based on reports of 24,406 people who have side effects when taking Janumet from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Status epilepticus?

Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure) is found to be associated with 666 drugs and 949 conditions by eHealthMe. Check the latest studies of Status epilepticus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

24,406 people reported to have side effects when taking Janumet.
Among them, 34 people (0.14%) have Status epilepticus.

Among these 34 people:

How long have people been on Janumet when they have Status epilepticus? *

What is the gender of people who have Status epilepticus when taking Janumet? *

female: 15.15 %
male: 84.85 %

What is the age of people who have Status epilepticus when taking Janumet? *

What are other drugs people take besides Janumet? *

What are other side effects people have besides Status epilepticus? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 29 people, 85.29%
Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 29 people, 85.29%
Eye Movement Disorder: 29 people, 85.29%
Oculogyric Crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction): 28 people, 82.35%
Muscle Spasms (muscle contraction): 28 people, 82.35%
Hypertensive Crisis: 2 people, 5.88%

What are the existing conditions these people have? *

Heart Disease: 29 people, 85.29%
High Blood Pressure: 29 people, 85.29%
Renal Disorder (kidney disease): 29 people, 85.29%
Cardiac Disorder: 29 people, 85.29%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 29 people, 85.29%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 29 people, 85.29%
Gout (uric acid crystals building up in the body): 29 people, 85.29%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 26 people, 76.47%
High Blood Cholesterol: 23 people, 67.65%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 23 people, 67.65%

* Approximation only. Some reports may have incomplete information.

Do you take Janumet and have Status epilepticus?

- Check whether Status epilepticus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Janumet:

Janumet (25,023 reports)

Status epilepticus treatments and more:

Status epilepticus (19,280 reports)

How severe was Status epilepticus and when was it recovered:

Status epilepticus in Janumet

Expand to all the drugs that have ingredients of metformin hydrochloride; sitagliptin phosphate:

Status epilepticus and drugs with ingredients of metformin hydrochloride; sitagliptin phosphate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Janumet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Status epilepticus:

Status epilepticus (666 drugs)

Browse all the conditions that are associated with Status epilepticus:

Status epilepticus (949 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride; sitagliptin phosphate (the active ingredients of Janumet) and Janumet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.