Janumet and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Janumet (metformin hydrochloride; sitagliptin phosphate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lipitor, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Janumet. It is created by eHealthMe based on reports of 24,406 people who have side effects when taking Janumet from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,639 drugs and 1,601 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Apr, 27, 2026

24,406 people reported to have side effects when taking Janumet.
Among them, 48 people (0.2%) have Thyroid function test abnormal.

Could Janumet cause Thyroid function test abnormal?

Among these 48 people:

How long have people been on Janumet when they have Thyroid function test abnormal? *

What is the gender of people who have Thyroid function test abnormal when taking Janumet? *

female: 68.75 %
male: 31.25 %

What is the age of people who have Thyroid function test abnormal when taking Janumet? *

What are other drugs people take besides Janumet? *

What are other side effects people have besides Thyroid function test abnormal? *

Weight Decreased: 22 people, 45.83%
Nausea (feeling of having an urge to vomit): 19 people, 39.58%
Malaise (a feeling of general discomfort or uneasiness): 16 people, 33.33%
High Blood Cholesterol: 14 people, 29.17%
Nausea And Vomiting: 13 people, 27.08%
Second Primary Malignancy (after getting cure a cancer, a new cancer development): 11 people, 22.92%
Colon Adenoma (non cancerous epithelial colon tumour having a glandular origin and structure): 11 people, 22.92%
Acute Kidney Failure: 11 people, 22.92%
Itching: 11 people, 22.92%
Pain: 10 people, 20.83%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 15 people, 31.25%
High Blood Pressure: 11 people, 22.92%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 11 people, 22.92%
High Blood Cholesterol: 10 people, 20.83%
Idiopathic Urticaria (allergic reactions, presence of hives with unknown cause): 6 people, 12.50%
Renal Cell Carcinoma (a kidney cancer): 5 people, 10.42%
Metastases To Gastrointestinal Tract (cancer spreads to gastrointestinal tract): 3 people, 6.25%
Blood Pressure Abnormal: 3 people, 6.25%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 6.25%
Pancreatic Carcinoma (pancreatic cancer): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Janumet and have Thyroid function test abnormal?

- Check whether Thyroid function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Janumet:

Janumet (25,023 reports)

Thyroid function test abnormal treatments and more:

Thyroid function test abnormal (69,463 reports)

How severe was Thyroid function test abnormal and when was it recovered:

Thyroid function test abnormal in Janumet

Expand to all the drugs that have ingredients of metformin hydrochloride; sitagliptin phosphate:

Thyroid function test abnormal and drugs with ingredients of metformin hydrochloride; sitagliptin phosphate (28 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Janumet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,639 drugs)

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,601 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride; sitagliptin phosphate (the active ingredients of Janumet) and Janumet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.