Jardiance and Multiple fractures - a phase IV clinical study of FDA data

Summary:

Multiple fractures is reported as a side effect among people who take Jardiance (empagliflozin), especially for people who are male, 60+ old, also take Viread, and have Hiv infection.

The phase IV clinical study analyzes which people have Multiple fractures when taking Jardiance. It is created by eHealthMe based on reports of 43,725 people who have side effects when taking Jardiance from the FDA, and is updated regularly.

What is Jardiance?

Jardiance has active ingredients of empagliflozin. It is often used in hyperglycemia. eHealthMe is studying from 44,459 Jardiance users. Check the latest studies of Jardiance.

What is Multiple fractures?

Multiple fractures is found to be associated with 730 drugs and 727 conditions by eHealthMe. Check the latest studies of Multiple fractures.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

43,725 people reported to have side effects when taking Jardiance.
Among them, 14 people (0.03%) have Multiple fractures.

$Could Jardiance cause Multiple fractures?$

Among these 14 people:

What is the gender of people who have Multiple fractures when taking Jardiance? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Multiple fractures when taking Jardiance? *

What are other drugs people take besides Jardiance? *

What are other side effects people have besides Multiple fractures? *

Pain: 8 people, 57.14%
Emotional Distress: 8 people, 57.14%
Bone Density Decreased: 8 people, 57.14%
Acute Kidney Failure: 7 people, 50.00%
Chronic Kidney Disease: 7 people, 50.00%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 6 people, 42.86%
Stress And Anxiety: 6 people, 42.86%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 5 people, 35.71%
Bone Loss: 5 people, 35.71%
Foot Fracture: 4 people, 28.57%

What are the existing conditions these people have? *

Hiv Infection: 8 people, 57.14%
Pain: 3 people, 21.43%
Diabetes: 3 people, 21.43%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 14.29%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 7.14%
Hypertriglyceridaemia (excess of triglycerides in the blood): 1 person, 7.14%
Arrhythmias (irregular heartbeat): 1 person, 7.14%
Atherosclerosis (disorder of the arteries): 1 person, 7.14%
Cardiac Disorder: 1 person, 7.14%
Cough: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Jardiance and have Multiple fractures?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Jardiance:

Jardiance (44,459 reports)

Browse all side effects of Jardiance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple fractures:

Multiple fractures (730 drugs)

Browse all the conditions that are associated with Multiple fractures:

Multiple fractures (727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on empagliflozin (the active ingredients of Jardiance) and Jardiance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.