Kadian and Osteopenia - a phase IV clinical study of FDA data

Summary:

Osteopenia is reported as a side effect among people who take Kadian (morphine sulfate), especially for people who are male, 60+ old, also take Cymbalta, and have Hiv infection.

The phase IV clinical study analyzes which people have Osteopenia when taking Kadian. It is created by eHealthMe based on reports of 22,916 people who have side effects when taking Kadian from the FDA, and is updated regularly.

What is Kadian?

Kadian has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 23,045 Kadian users. Check the latest studies of Kadian.

What is Osteopenia?

Osteopenia (a condition where bone mineral density is lower than normal) is found to be associated with 1,434 drugs and 1,172 conditions by eHealthMe. Check the latest studies of Osteopenia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

22,916 people reported to have side effects when taking Kadian.
Among them, 21 people (0.09%) have Osteopenia.

Among these 21 people:

What is the gender of people who have Osteopenia when taking Kadian? *

female: 47.62 %
male: 52.38 %

What is the age of people who have Osteopenia when taking Kadian? *

What are other drugs people take besides Kadian? *

What are other side effects people have besides Osteopenia? *

Osteoporosis (bones weak and more likely to break): 14 people, 66.67%
Hearing Loss: 11 people, 52.38%
Sinusitis (inflammation of sinus): 11 people, 52.38%
Infection: 11 people, 52.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 52.38%
Fall: 11 people, 52.38%
Neuropathy Peripheral (surface nerve damage): 11 people, 52.38%
Osteomyelitis (infection of bone): 11 people, 52.38%
Pneumonia: 11 people, 52.38%
Fatigue (feeling of tiredness): 10 people, 47.62%

What are the existing conditions these people have? *

Hiv Infection: 10 people, 47.62%
Osteoporosis (bones weak and more likely to break): 5 people, 23.81%
Hepatitis B: 3 people, 14.29%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Kadian and have Osteopenia?

- Check whether Osteopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Kadian:

Kadian (23,045 reports)

Osteopenia treatments and more:

Osteopenia (46,948 reports)

Browse all side effects of Kadian:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteopenia:

Osteopenia (1,434 drugs)

Browse all the conditions that are associated with Osteopenia:

Osteopenia (1,172 conditions)

Related publications that referenced our studies

Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Kadian) and Kadian (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.