Kaletra and Hypothermia - a phase IV clinical study of FDA data

Summary:

Hypothermia is reported as a side effect among people who take Kaletra (lopinavir; ritonavir), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Videx, and have Thrombophlebitis.

The phase IV clinical study analyzes which people have Hypothermia when taking Kaletra. It is created by eHealthMe based on reports of 22,879 people who have side effects when taking Kaletra from the FDA, and is updated regularly.

What is Kaletra?

Kaletra has active ingredients of lopinavir; ritonavir. It is often used in hiv infection. eHealthMe is studying from 23,070 Kaletra users. Check the latest studies of Kaletra.

What is Hypothermia?

Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions) is found to be associated with 774 drugs and 997 conditions by eHealthMe. Check the latest studies of Hypothermia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

22,879 people reported to have side effects when taking Kaletra.
Among them, 17 people (0.07%) have Hypothermia.

Among these 17 people:

How long have people been on Kaletra when they have Hypothermia? *

What is the gender of people who have Hypothermia when taking Kaletra? *

female: 18.75 %
male: 81.25 %

What is the age of people who have Hypothermia when taking Kaletra? *

What are other drugs people take besides Kaletra? *

What are other side effects people have besides Hypothermia? *

Acute Kidney Failure: 6 people, 35.29%
Hypotension (abnormally low blood pressure): 6 people, 35.29%
Thrombocytopenia (decrease of platelets in blood): 4 people, 23.53%
Lactic Acidosis (low ph in body tissues): 4 people, 23.53%
Pancreatitis (inflammation of pancreas): 4 people, 23.53%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 4 people, 23.53%
Septic Shock (shock due to blood infection): 4 people, 23.53%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 17.65%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 3 people, 17.65%
Nausea And Vomiting: 3 people, 17.65%

What are the existing conditions these people have? *

Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 5 people, 29.41%
Lung Disorder (lung disease): 4 people, 23.53%
Drug Exposure During Pregnancy: 1 person, 5.88%
Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Kaletra and have Hypothermia?

- Check whether Hypothermia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Kaletra:

Kaletra (23,070 reports)

Hypothermia treatments and more:

Hypothermia (12,298 reports)

Browse all side effects of Kaletra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothermia:

Hypothermia (774 drugs)

Browse all the conditions that are associated with Hypothermia:

Hypothermia (997 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lopinavir; ritonavir (the active ingredients of Kaletra) and Kaletra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.