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Keppra and Pre-eclampsia - a phase IV clinical study of FDA data

Summary:

Pre-eclampsia is reported as a side effect among people who take Keppra (levetiracetam), especially for people who are 30-39 old, have been taking the drug for < 1 month also take Trileptal, and have Birth control.

The phase IV clinical study analyzes which people have Pre-eclampsia when taking Keppra. It is created by eHealthMe based on reports of 70,297 people who have side effects when taking Keppra from the FDA, and is updated regularly.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

What is Pre-eclampsia?

Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman) is found to be associated with 392 drugs and 577 conditions by eHealthMe. Check the latest studies of Pre-eclampsia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

70,297 people reported to have side effects when taking Keppra.
Among them, 51 people (0.07%) have Pre-eclampsia.

Could Keppra cause Pre-eclampsia?

Among these 51 people:

How long have people been on Keppra when they have Pre-eclampsia? *

  • < 1 month: 50 %
  • 1 - 6 months: 30 %
  • 6 - 12 months: 20 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Pre-eclampsia when taking Keppra? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.27 %
  • 20-29: 27.27 %
  • 30-39: 56.82 %
  • 40-49: 13.64 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Keppra? *

  1. Folic Acid: 7 people, 13.73%
  2. Lamictal: 7 people, 13.73%
  3. Vimpat: 7 people, 13.73%
  4. Trileptal: 7 people, 13.73%
  5. Prednisone: 6 people, 11.76%
  6. Flovent: 5 people, 9.80%
  7. Biaxin: 5 people, 9.80%
  8. Fioricet: 5 people, 9.80%
  9. Pristiq: 5 people, 9.80%
  10. Temazepam: 5 people, 9.80%

What are other side effects people have besides Pre-eclampsia? *

  1. Birth Control: 14 people, 27.45%
  2. Drug Exposure During Pregnancy: 14 people, 27.45%
  3. Premature Delivery: 12 people, 23.53%
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 11 people, 21.57%
  5. Fever: 10 people, 19.61%
  6. Maternal Exposure During Pregnancy (use of substance during pregnancy): 10 people, 19.61%
  7. Premature Labor: 7 people, 13.73%
  8. High Blood Pressure: 6 people, 11.76%
  9. Nosebleed (bleeding from nose): 6 people, 11.76%
  10. Gamma-Glutamyltransferase Increased: 5 people, 9.80%

What are the existing conditions these people have? *

  1. Birth Control: 6 people, 11.76%
  2. Insomnia (sleeplessness): 5 people, 9.80%
  3. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 5 people, 9.80%
  4. Sinusitis (inflammation of sinus): 5 people, 9.80%
  5. Sinus Congestion (blockage of sinus): 5 people, 9.80%
  6. Post-Traumatic Stress Disorder: 5 people, 9.80%
  7. Asthma: 5 people, 9.80%
  8. Juvenile Myoclonic Epilepsy (childhood epilepsy occurring early in morning affecting 12 to 18 years): 5 people, 9.80%
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 5 people, 9.80%
  10. Blood Pressure Abnormal: 4 people, 7.84%

* Approximation only. Some reports may have incomplete information.

Do you take Keppra and have Pre-eclampsia?

- Check whether Pre-eclampsia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Keppra:

Pre-eclampsia treatments and more:

How severe was Pre-eclampsia and when was it recovered:

Expand to all the drugs that have ingredients of levetiracetam:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Keppra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pre-eclampsia:

Browse all the conditions that are associated with Pre-eclampsia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on levetiracetam (the active ingredients of Keppra) and Keppra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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