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Keppra and Terminal state - a phase IV clinical study of FDA data

Summary:

Terminal state is reported as a side effect among people who take Keppra (levetiracetam), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Tegretol, and have Convulsion.

The phase IV clinical study analyzes which people have Terminal state when taking Keppra. It is created by eHealthMe based on reports of 70,297 people who have side effects when taking Keppra from the FDA, and is updated regularly.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

What is Terminal state?

Terminal state (the transitional states between life and biological death) is found to be associated with 371 drugs and 562 conditions by eHealthMe. Check the latest studies of Terminal state.

On Aug, 12, 2026

70,297 people reported to have side effects when taking Keppra.
Among them, 19 people (0.03%) have Terminal state.

Could Keppra cause Terminal state?

Among these 19 people:

How long have people been on Keppra when they have Terminal state? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Terminal state when taking Keppra? *

  • female: 17.65 %
  • male: 82.35 %

What is the age of people who have Terminal state when taking Keppra? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 37.5 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 0.0 %
  • 60+: 50.0 %

What are other drugs people take besides Keppra? *

  1. Tegretol: 4 people, 21.05%
  2. Zofran: 3 people, 15.79%
  3. Omeprazole: 3 people, 15.79%
  4. Nexium: 2 people, 10.53%
  5. Myrbetriq: 2 people, 10.53%
  6. Miralax: 2 people, 10.53%
  7. Losartan Potassium: 2 people, 10.53%
  8. Ipratropium Bromide: 2 people, 10.53%
  9. Hydrocortisone: 2 people, 10.53%
  10. Fluticasone Propionate: 2 people, 10.53%

What are other side effects people have besides Terminal state? *

  1. Swallowing Difficulty: 3 people, 15.79%
  2. Hospitalisation: 2 people, 10.53%
  3. Bone Marrow Failure: 2 people, 10.53%
  4. Head Injury: 2 people, 10.53%
  5. Leukaemia Recurrent (repeat cancer of bone marrow or blood cells): 2 people, 10.53%
  6. Feeling Abnormal: 2 people, 10.53%
  7. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 10.53%
  8. Pneumonia: 2 people, 10.53%
  9. Urinary Tract Infection: 2 people, 10.53%
  10. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 10.53%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 10.53%
  2. Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 10.53%
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 10.53%
  4. Renal Cell Carcinoma (a kidney cancer): 1 person, 5.26%
  5. Pneumonia: 1 person, 5.26%
  6. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 5.26%
  7. Idiopathic Thrombocytopenic Purpura (Itp) (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 5.26%
  8. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Keppra and have Terminal state?

- Check whether Terminal state is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Keppra:

Terminal state treatments and more:

How severe was Terminal state and when was it recovered:

Expand to all the drugs that have ingredients of levetiracetam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Keppra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Terminal state:

Browse all the conditions that are associated with Terminal state:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on levetiracetam (the active ingredients of Keppra) and Keppra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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