Ketamine hcl and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Ketamine hcl (ketamine hydrochloride), especially for people who are female, 10-19 old, also take Midazolam, and have Convulsion.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Ketamine hcl. It is created by eHealthMe based on reports of 1,742 people who have side effects when taking Ketamine hcl from the FDA, and is updated regularly.

What is Ketamine hcl?

Ketamine hcl has active ingredients of ketamine hydrochloride. It is often used in pain. eHealthMe is studying from 1,851 Ketamine hcl users. Check the latest studies of Ketamine hcl.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,617 drugs and 2,600 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 27, 2026

1,742 people reported to have side effects when taking Ketamine hcl.
Among them, 14 people (0.8%) have Hypothyroidism.

Could Ketamine hcl cause Hypothyroidism?

Among these 14 people:

What is the gender of people who have Hypothyroidism when taking Ketamine hcl? *

female: 76.92 %
male: 23.08 %

What is the age of people who have Hypothyroidism when taking Ketamine hcl? *

What are other drugs people take besides Ketamine hcl? *

What are other side effects people have besides Hypothyroidism? *

Drug Rash With Eosinophilia And Systemic Symptoms (adverse drug reactions with rash): 8 people, 57.14%
Hyperthyroidism (over activity of the thyroid gland): 8 people, 57.14%
Rashes (redness): 7 people, 50.00%
Fever: 6 people, 42.86%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 4 people, 28.57%
Cytomegalovirus Infection: 4 people, 28.57%
Heart Rate Increased: 4 people, 28.57%
Respiratory Rate Increased (excess breathing rate/min): 4 people, 28.57%
Chapped Lips (cracking, fissuring, and peeling of the skin f lip): 4 people, 28.57%
Hepatic Function Abnormal: 4 people, 28.57%

What are the existing conditions these people have? *

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 50.00%
Sedation: 6 people, 42.86%
Drug Rash With Eosinophilia And Systemic Symptoms (adverse drug reactions with rash): 4 people, 28.57%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 2 people, 14.29%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 7.14%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.14%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 7.14%
Depression: 1 person, 7.14%
Agitation (state of anxiety or nervous excitement): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Ketamine hcl and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ketamine hcl:

Ketamine hcl (1,851 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,071 reports)

Browse all side effects of Ketamine hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,617 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,600 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on ketamine hydrochloride (the active ingredients of Ketamine hcl) and Ketamine hcl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.