Ketoconazole and Respiratory distress - a phase IV clinical study of FDA data

Summary:

Respiratory distress is reported as a side effect among people who take Ketoconazole (ketoconazole), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Oxycodone And Acetaminophen, and have Muscle spasticity.

The phase IV clinical study analyzes which people have Respiratory distress when taking Ketoconazole. It is created by eHealthMe based on reports of 15,751 people who have side effects when taking Ketoconazole from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Respiratory distress?

Respiratory distress (difficulty in breathing) is found to be associated with 1,566 drugs and 1,869 conditions by eHealthMe. Check the latest studies of Respiratory distress.

On Jul, 03, 2026

15,751 people reported to have side effects when taking Ketoconazole.
Among them, 37 people (0.23%) have Respiratory distress.

Could Ketoconazole cause Respiratory distress?

Among these 37 people:

How long have people been on Ketoconazole when they have Respiratory distress? *

What is the gender of people who have Respiratory distress when taking Ketoconazole? *

female: 28.57 %
male: 71.43 %

What is the age of people who have Respiratory distress when taking Ketoconazole? *

What are other drugs people take besides Ketoconazole? *

Oxycodone And Acetaminophen: 10 people, 27.03%
Acetaminophen: 9 people, 24.32%
Epinephrine: 9 people, 24.32%
Triamcinolone: 9 people, 24.32%
Advair Hfa: 7 people, 18.92%
Nystatin: 7 people, 18.92%
Spironolactone: 6 people, 16.22%
Aspirin: 6 people, 16.22%
Hydrocortisone: 6 people, 16.22%
Lioresal: 6 people, 16.22%

What are other side effects people have besides Respiratory distress? *

Dyspnea (difficult or laboured breathing): 14 people, 37.84%
Oedema Peripheral (superficial swelling): 7 people, 18.92%
Urinary Retention (the inability to completely or partially empty the bladder): 7 people, 18.92%
Cardiac Failure Congestive: 7 people, 18.92%
Abdominal Distension: 6 people, 16.22%
Muscle Spasms (muscle contraction): 6 people, 16.22%
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 6 people, 16.22%
Skin Abscess: 6 people, 16.22%
Exostosis (formation of new bone on the surface of a bone): 6 people, 16.22%
Muscle Tightness: 6 people, 16.22%

What are the existing conditions these people have? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 13.51%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 13.51%
Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 8.11%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 8.11%
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 2 people, 5.41%
Pleurisy (inflammation of the pleurae, which causes pain when breathing): 2 people, 5.41%
Trismus (reduced opening of the jaws): 1 person, 2.70%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 2.70%
Ileal Perforation: 1 person, 2.70%
Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Ketoconazole and have Respiratory distress?

- Check whether Respiratory distress is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ketoconazole:

Ketoconazole (16,014 reports)

Browse all side effects of Ketoconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Respiratory distress:

Respiratory distress (1,566 drugs)

Browse all the conditions that are associated with Respiratory distress:

Respiratory distress (1,869 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ketoconazole (the active ingredients of Ketoconazole) and Ketoconazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.