Kionex and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Kionex (sodium polystyrene sulfonate), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Veltassa, and have Hyperkalemia.

The study is created by eHealthMe based on reports of 474 people who have side effects when taking Kionex from the FDA, and is updated regularly.

What is Kionex?

Kionex has active ingredients of sodium polystyrene sulfonate. eHealthMe is studying from 478 Kionex users. Check the latest studies of Kionex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

474 people reported to have side effects when taking Kionex.
Among them, 34 people (7.17%) died.

Among these 34 people:

How long have people been on Kionex when they died? *

What is the gender of people who died when taking Kionex? *

female: 43.33 %
male: 56.67 %

What is the age of people who died when taking Kionex? *

What are other drugs people take besides Kionex? *

What are other side effects people have before they died? *

Chronic Kidney Disease: 5 people, 14.71%
Nausea (feeling of having an urge to vomit): 5 people, 14.71%
Nausea And Vomiting: 3 people, 8.82%
Dyspnea (difficult or laboured breathing): 3 people, 8.82%
Pain: 3 people, 8.82%
Hyperkalemia (damage to or disease of the kidney): 3 people, 8.82%
Fatigue (feeling of tiredness): 2 people, 5.88%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 5.88%
Diarrhea: 2 people, 5.88%
Chest Pain: 2 people, 5.88%

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 18 people, 52.94%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 11.76%
Pain: 3 people, 8.82%
High Blood Cholesterol: 2 people, 5.88%
Stress And Anxiety: 2 people, 5.88%
Blood Pressure Abnormal: 2 people, 5.88%
Diabetes: 1 person, 2.94%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 2.94%
Fever: 1 person, 2.94%
Fainting (loss of consciousness and postural tone): 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Kionex:

Kionex (478 reports)

Expand to all the drugs that have ingredients of sodium polystyrene sulfonate:

Death and drugs with ingredients of sodium polystyrene sulfonate (263 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Kionex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,107 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sodium polystyrene sulfonate (the active ingredients of Kionex) and Kionex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.