Kisqali and International normalised ratio increased - a phase IV clinical study of FDA data

Summary:

International normalised ratio increased is reported as a side effect among people who take Kisqali (ribociclib succinate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Amlodipine, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have International normalised ratio increased when taking Kisqali. It is created by eHealthMe based on reports of 25,037 people who have side effects when taking Kisqali from the FDA, and is updated regularly.

What is Kisqali?

Kisqali has active ingredients of ribociclib succinate. eHealthMe is studying from 25,050 Kisqali users. Check the latest studies of Kisqali.

What is International normalised ratio increased?

International normalised ratio increased is found to be associated with 1,333 drugs and 1,727 conditions by eHealthMe. Check the latest studies of International normalised ratio increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

25,037 people reported to have side effects when taking Kisqali.
Among them, 15 people (0.06%) have International normalised ratio increased.

Could Kisqali cause International normalised ratio increased?

Among these 15 people:

How long have people been on Kisqali when they have International normalised ratio increased? *

What is the gender of people who have International normalised ratio increased when taking Kisqali? *

female: 100 %
male: 0.0 %

What is the age of people who have International normalised ratio increased when taking Kisqali? *

What are other drugs people take besides Kisqali? *

What are other side effects people have besides International normalised ratio increased? *

Malaise (a feeling of general discomfort or uneasiness): 12 people, 80.00%
Diarrhea: 9 people, 60.00%
Dyspnea (difficult or laboured breathing): 9 people, 60.00%
Blood Creatinine Increased: 8 people, 53.33%
Neutropenic Sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection): 8 people, 53.33%
Bone Marrow Failure: 8 people, 53.33%
Blood Urea Increased: 8 people, 53.33%
Blood Phosphorus Increased: 8 people, 53.33%
Blood Fibrinogen Increased: 8 people, 53.33%
Activated Partial Thromboplastin Time Prolonged: 8 people, 53.33%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 14 people, 93.33%
Radiation Associated Pain (pain due to radiation): 8 people, 53.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 26.67%
High Blood Pressure: 3 people, 20.00%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 13.33%
Breast Cancer: 2 people, 13.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
Pain: 1 person, 6.67%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 6.67%
Insomnia (sleeplessness): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Kisqali and have International normalised ratio increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Kisqali:

Kisqali (25,050 reports)

International normalised ratio increased treatments and more:

International normalised ratio increased (40,071 reports)

How severe was International normalised ratio increased and when was it recovered:

International normalised ratio increased in Kisqali

Expand to all the drugs that have ingredients of ribociclib succinate:

International normalised ratio increased and drugs with ingredients of ribociclib succinate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Kisqali:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with International normalised ratio increased:

International normalised ratio increased (1,333 drugs)

Browse all the conditions that are associated with International normalised ratio increased:

International normalised ratio increased (1,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ribociclib succinate (the active ingredients of Kisqali) and Kisqali (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.