Klonopin and Post concussion syndrome - a phase IV clinical study of FDA data

Summary:

Post concussion syndrome is reported as a side effect among people who take Klonopin (clonazepam), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Fioricet, and have Narcolepsy.

The phase IV clinical study analyzes which people have Post concussion syndrome when taking Klonopin. It is created by eHealthMe based on reports of 59,526 people who have side effects when taking Klonopin from the FDA, and is updated regularly.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

What is Post concussion syndrome?

Post concussion syndrome is found to be associated with 99 drugs and 222 conditions by eHealthMe. Check the latest studies of Post concussion syndrome.



On Jul, 16, 2026

59,526 people reported to have side effects when taking Klonopin.
Among them, 26 people (0.04%) have Post concussion syndrome.

Could Klonopin cause Post concussion syndrome?

Among these 26 people:

How long have people been on Klonopin when they have Post concussion syndrome? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Post concussion syndrome when taking Klonopin? *

  • female: 61.54 %
  • male: 38.46 %

What is the age of people who have Post concussion syndrome when taking Klonopin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 8.33 %
  • 20-29: 45.83 %
  • 30-39: 0.0 %
  • 40-49: 8.33 %
  • 50-59: 29.17 %
  • 60+: 8.33 %

What are other drugs people take besides Klonopin? *

  1. Neurontin: 12 people, 46.15%
  2. Fioricet: 12 people, 46.15%
  3. Promethazine: 11 people, 42.31%
  4. Viibryd: 11 people, 42.31%
  5. Xyrem: 10 people, 38.46%
  6. Adderall: 8 people, 30.77%
  7. Ambien: 8 people, 30.77%
  8. Colace: 6 people, 23.08%
  9. Lexapro: 6 people, 23.08%
  10. Migranal: 6 people, 23.08%

What are other side effects people have besides Post concussion syndrome? *

  1. Concussion (short loss of normal brain function in response to a head injury): 16 people, 61.54%
  2. Headache (pain in head): 13 people, 50.00%
  3. Pain: 12 people, 46.15%
  4. Memory Loss: 9 people, 34.62%
  5. Suicidal Ideation: 9 people, 34.62%
  6. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 8 people, 30.77%
  7. Head Injury: 8 people, 30.77%
  8. Joint Pain: 7 people, 26.92%
  9. General Physical Health Deterioration (weak health status): 7 people, 26.92%
  10. Gait Disturbance: 7 people, 26.92%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 50.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 23.08%
  3. High Blood Pressure: 6 people, 23.08%
  4. Multiple Myeloma (cancer of the plasma cells): 6 people, 23.08%
  5. Insomnia (sleeplessness): 4 people, 15.38%
  6. Depression: 3 people, 11.54%
  7. Migraine (headache): 2 people, 7.69%
  8. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 7.69%
  9. Post-Traumatic Stress Disorder: 2 people, 7.69%
  10. Joint Pain: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Klonopin and have Post concussion syndrome?

- Check whether Post concussion syndrome is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Klonopin:

Post concussion syndrome treatments and more:

How severe was Post concussion syndrome and when was it recovered:

Expand to all the drugs that have ingredients of clonazepam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Klonopin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Post concussion syndrome:

Browse all the conditions that are associated with Post concussion syndrome:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clonazepam (the active ingredients of Klonopin) and Klonopin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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