Klonopin and Spider vein - a phase IV clinical study of FDA data

Summary:

Spider vein is reported as a side effect among people who take Klonopin (clonazepam), especially for people who are male, 60+ old, also take Gralise, and have Pain.

The phase IV clinical study analyzes which people have Spider vein when taking Klonopin. It is created by eHealthMe based on reports of 59,526 people who have side effects when taking Klonopin from the FDA, and is updated regularly.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

What is Spider vein?

Spider vein (small dilated blood vessels near the surface of the skin) is found to be associated with 109 drugs and 243 conditions by eHealthMe. Check the latest studies of Spider vein.



On Jul, 19, 2026

59,526 people reported to have side effects when taking Klonopin.
Among them, 14 people (0.02%) have Spider vein.

Could Klonopin cause Spider vein?

Among these 14 people:

What is the gender of people who have Spider vein when taking Klonopin? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Spider vein when taking Klonopin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 33.33 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 8.33 %
  • 60+: 58.33 %

What are other drugs people take besides Klonopin? *

  1. Imbruvica: 6 people, 42.86%
  2. Coreg: 6 people, 42.86%
  3. Lortab: 6 people, 42.86%
  4. Keppra: 6 people, 42.86%
  5. Topamax: 6 people, 42.86%
  6. Carbatrol: 6 people, 42.86%
  7. Gralise: 6 people, 42.86%
  8. Dilantin: 5 people, 35.71%
  9. Oxycontin: 5 people, 35.71%
  10. Hydrocodone: 4 people, 28.57%

What are other side effects people have besides Spider vein? *

  1. Rashes (redness): 11 people, 78.57%
  2. Gait Disturbance: 10 people, 71.43%
  3. Loss Of Consciousness: 7 people, 50.00%
  4. Wound: 6 people, 42.86%
  5. Skin Discoloration: 6 people, 42.86%
  6. Adverse Event: 6 people, 42.86%
  7. Emotional Disorder: 6 people, 42.86%
  8. Head Injury: 6 people, 42.86%
  9. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 6 people, 42.86%
  10. Increased Tendency To Bruise (increased tendency to injure the underlying soft tissue or bone): 6 people, 42.86%

What are the existing conditions these people have? *

  1. Pain: 7 people, 50.00%
  2. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 6 people, 42.86%
  3. Breakthrough Pain: 6 people, 42.86%
  4. Burkitt Lymphoma (cancer of the lymphatic system): 6 people, 42.86%
  5. Depression: 6 people, 42.86%
  6. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 42.86%
  7. Abdominal Pain: 6 people, 42.86%
  8. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 42.86%
  9. Panic Reaction: 4 people, 28.57%
  10. Cerebral Disorder (brain disease): 4 people, 28.57%

* Approximation only. Some reports may have incomplete information.

Do you take Klonopin and have Spider vein?

- Check whether Spider vein is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Klonopin:

Spider vein treatments and more:

How severe was Spider vein and when was it recovered:

Expand to all the drugs that have ingredients of clonazepam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Klonopin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spider vein:

Browse all the conditions that are associated with Spider vein:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clonazepam (the active ingredients of Klonopin) and Klonopin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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