Konakion and Cardiac failure - a phase IV clinical study of FDA data

Summary:

Cardiac failure is reported as a side effect among people who take Konakion (phytonadione), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have High blood pressure.

The phase IV clinical study analyzes which people have Cardiac failure when taking Konakion. It is created by eHealthMe based on reports of 1,341 people who have side effects when taking Konakion from the FDA, and is updated regularly.

What is Konakion?

Konakion has active ingredients of phytonadione. eHealthMe is studying from 1,342 Konakion users. Check the latest studies of Konakion.

What is Cardiac failure?

Cardiac failure is found to be associated with 2,058 drugs and 2,210 conditions by eHealthMe. Check the latest studies of Cardiac failure.

On Jul, 06, 2026

1,341 people reported to have side effects when taking Konakion.
Among them, 51 people (3.8%) have Cardiac failure.

Among these 51 people:

How long have people been on Konakion when they have Cardiac failure? *

What is the gender of people who have Cardiac failure when taking Konakion? *

female: 60 %
male: 40 %

What is the age of people who have Cardiac failure when taking Konakion? *

What are other drugs people take besides Konakion? *

What are other side effects people have besides Cardiac failure? *

Pneumonia: 9 people, 17.65%
Blood Creatinine Increased: 6 people, 11.76%
Erythema Multiforme (a type of hypersensitivity reaction): 6 people, 11.76%
Hypotension (abnormally low blood pressure): 6 people, 11.76%
Dyspnea (difficult or laboured breathing): 6 people, 11.76%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 9.80%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 9.80%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 5 people, 9.80%
Electrocardiogram Qt Prolonged: 5 people, 9.80%
Cytolytic Hepatitis (dissolution or destruction of a liver cell): 5 people, 9.80%

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 17.65%
Pain: 6 people, 11.76%
High Blood Cholesterol: 5 people, 9.80%
Infection: 4 people, 7.84%
Hypokalemia (low potassium): 4 people, 7.84%
Multiple Myeloma (cancer of the plasma cells): 3 people, 5.88%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 5.88%
Oedema (fluid collection in tissue): 3 people, 5.88%
Oedema Peripheral (superficial swelling): 3 people, 5.88%
Hyperkalemia (damage to or disease of the kidney): 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Konakion and have Cardiac failure?

- Check whether Cardiac failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Konakion:

Konakion (1,342 reports)

Cardiac failure treatments and more:

Cardiac failure (147,157 reports)

Browse all side effects of Konakion:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac failure:

Cardiac failure (2,058 drugs)

Browse all the conditions that are associated with Cardiac failure:

Cardiac failure (2,210 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on phytonadione (the active ingredients of Konakion) and Konakion (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.