Kynamro and Fatigue - a phase IV clinical study of FDA data

Summary:

Fatigue is reported as a side effect among people who take Kynamro (mipomersen sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Zetia, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Fatigue when taking Kynamro. It is created by eHealthMe based on reports of 288 people who have side effects when taking Kynamro from the FDA, and is updated regularly.

What is Kynamro?

Kynamro has active ingredients of mipomersen sodium. eHealthMe is studying from 288 Kynamro users. Check the latest studies of Kynamro.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 4,025 drugs and 6,378 conditions by eHealthMe. Check the latest studies of Fatigue.

On May, 13, 2026

288 people reported to have side effects when taking Kynamro.
Among them, 35 people (12.15%) have Fatigue.

Among these 35 people:

How long have people been on Kynamro when they have Fatigue? *

What is the gender of people who have Fatigue when taking Kynamro? *

female: 74.29 %
male: 25.71 %

What is the age of people who have Fatigue when taking Kynamro? *

What are other drugs people take besides Kynamro? *

What are other side effects people have besides Fatigue? *

Injection Site Pain: 20 people, 57.14%
Injection Site Erythema (redness at injection site): 16 people, 45.71%
Hepatic Enzyme Increased: 11 people, 31.43%
Injection Site Swelling: 10 people, 28.57%
Injection Site Discoloration: 9 people, 25.71%
Influenza Like Illness: 9 people, 25.71%
Injection Site Bruising: 9 people, 25.71%
Nausea (feeling of having an urge to vomit): 8 people, 22.86%
Injection Site Pruritus (severe itching at injection site): 7 people, 20.00%
Muscle Aches (muscle pain): 6 people, 17.14%

What are the existing conditions these people have? *

High Blood Cholesterol: 11 people, 31.43%
Migraine (headache): 5 people, 14.29%
Cardiac Disorder: 3 people, 8.57%
Pain: 3 people, 8.57%
Chest Pain: 3 people, 8.57%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 5.71%
Hypersensitivity: 2 people, 5.71%
Platelet Count Increased: 2 people, 5.71%
Oesophageal Spasm (contraction of oesophagus): 2 people, 5.71%
High Blood Pressure: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Kynamro and have Fatigue?

- Check whether Fatigue is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Kynamro:

Kynamro (288 reports)

Fatigue treatments and more:

Fatigue (967,531 reports)

Browse all side effects of Kynamro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue:

Fatigue (4,025 drugs)

Browse all the conditions that are associated with Fatigue:

Fatigue (6,378 conditions)

Related publications that referenced our studies

Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on mipomersen sodium (the active ingredients of Kynamro) and Kynamro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.