Lac-hydrin and Spinal osteoarthritis - a phase IV clinical study of FDA data

Summary:

Spinal osteoarthritis is reported as a side effect among people who take Lac-hydrin (ammonium lactate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Celebrex, and have Metastases to bone.

The phase IV clinical study analyzes which people have Spinal osteoarthritis when taking Lac-hydrin. It is created by eHealthMe based on reports of 531 people who have side effects when taking Lac-hydrin from the FDA, and is updated regularly.

What is Lac-hydrin?

Lac-hydrin has active ingredients of ammonium lactate. eHealthMe is studying from 534 Lac-hydrin users. Check the latest studies of Lac-hydrin.

What is Spinal osteoarthritis?

Spinal osteoarthritis (joint cartilage loss in spine) is found to be associated with 1,421 drugs and 1,124 conditions by eHealthMe. Check the latest studies of Spinal osteoarthritis.



On Jul, 19, 2026

531 people reported to have side effects when taking Lac-hydrin.
Among them, 16 people (3.01%) have Spinal osteoarthritis.

Could Lac-hydrin cause Spinal osteoarthritis?

Among these 16 people:

How long have people been on Lac-hydrin when they have Spinal osteoarthritis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Spinal osteoarthritis when taking Lac-hydrin? *

  • female: 93.75 %
  • male: 6.25 %

What is the age of people who have Spinal osteoarthritis when taking Lac-hydrin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 100 %
  • 60+: 0.0 %

What are other drugs people take besides Lac-hydrin? *

  1. Prilosec: 16 people, 100.00%
  2. Nasonex: 16 people, 100.00%
  3. Celebrex: 16 people, 100.00%
  4. Cymbalta: 15 people, 93.75%
  5. Selenium: 15 people, 93.75%
  6. Vioxx: 15 people, 93.75%
  7. Protonix: 14 people, 87.50%
  8. Simvastatin: 14 people, 87.50%
  9. Glutamine: 14 people, 87.50%
  10. Reglan: 14 people, 87.50%

What are other side effects people have besides Spinal osteoarthritis? *

  1. Chest Pain: 16 people, 100.00%
  2. Chronic Renal Failure (kidney failure): 15 people, 93.75%
  3. Osteoporosis (bones weak and more likely to break): 15 people, 93.75%
  4. Gastritis (inflammation of stomach): 15 people, 93.75%
  5. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 15 people, 93.75%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 93.75%
  7. Scoliosis (a medical condition in which a person's spine is curved from side to side): 15 people, 93.75%
  8. Sinusitis (inflammation of sinus): 15 people, 93.75%
  9. Weight Increased: 15 people, 93.75%
  10. High Blood Cholesterol: 15 people, 93.75%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 14 people, 87.50%
  2. High Blood Pressure: 2 people, 12.50%
  3. Breast Cancer Metastatic: 2 people, 12.50%
  4. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.25%
  5. Dizziness: 1 person, 6.25%
  6. Gastritis (inflammation of stomach): 1 person, 6.25%
  7. Fungal Infection: 1 person, 6.25%
  8. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 6.25%
  9. Dyspnea (difficult or laboured breathing): 1 person, 6.25%
  10. Depression: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lac-hydrin and have Spinal osteoarthritis?

- Check whether Spinal osteoarthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lac-hydrin:

Spinal osteoarthritis treatments and more:

How severe was Spinal osteoarthritis and when was it recovered:

Expand to all the drugs that have ingredients of ammonium lactate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lac-hydrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal osteoarthritis:

Browse all the conditions that are associated with Spinal osteoarthritis:


How the study uses the data?

The study uses data from the FDA. It is based on ammonium lactate (the active ingredients of Lac-hydrin) and Lac-hydrin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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