Lacosamide and Hepatic enzyme increased - a phase IV clinical study of FDA data

Summary:

Hepatic enzyme increased is reported as a side effect among people who take Lacosamide (lacosamide), especially for people who are female, 20-29 old, have been taking the drug for 1 - 2 years also take Perampanel, and have Seizures.

The phase IV clinical study analyzes which people have Hepatic enzyme increased when taking Lacosamide. It is created by eHealthMe based on reports of 16,542 people who have side effects when taking Lacosamide from the FDA, and is updated regularly.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

What is Hepatic enzyme increased?

Hepatic enzyme increased is found to be associated with 1,884 drugs and 2,016 conditions by eHealthMe. Check the latest studies of Hepatic enzyme increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

16,542 people reported to have side effects when taking Lacosamide.
Among them, 71 people (0.43%) have Hepatic enzyme increased.

Could Lacosamide cause Hepatic enzyme increased?

Among these 71 people:

How long have people been on Lacosamide when they have Hepatic enzyme increased? *

What is the gender of people who have Hepatic enzyme increased when taking Lacosamide? *

female: 75 %
male: 25 %

What is the age of people who have Hepatic enzyme increased when taking Lacosamide? *

What are other drugs people take besides Lacosamide? *

What are other side effects people have besides Hepatic enzyme increased? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 35 people, 49.30%
Dizziness: 28 people, 39.44%
Headache (pain in head): 27 people, 38.03%
Weight Increased: 26 people, 36.62%
Tremor (trembling or shaking movements in one or more parts of your body): 25 people, 35.21%
Lipids Abnormal: 25 people, 35.21%
Gamma-Glutamyltransferase Increased: 11 people, 15.49%
Depression: 10 people, 14.08%
Nausea (feeling of having an urge to vomit): 10 people, 14.08%
Stress And Anxiety: 9 people, 12.68%

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 27 people, 38.03%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 7 people, 9.86%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 4.23%
Partial Seizures (seizures which affect only a part of the brain at onset): 3 people, 4.23%
Myoclonic Epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs): 3 people, 4.23%
High Blood Pressure: 3 people, 4.23%
Agitation (state of anxiety or nervous excitement): 2 people, 2.82%
Aortic Valve Disease: 2 people, 2.82%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 2.82%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 2.82%

* Approximation only. Some reports may have incomplete information.

Do you take Lacosamide and have Hepatic enzyme increased?

- Check whether Hepatic enzyme increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lacosamide:

Lacosamide (16,601 reports)

Browse all side effects of Lacosamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic enzyme increased:

Hepatic enzyme increased (1,884 drugs)

Browse all the conditions that are associated with Hepatic enzyme increased:

Hepatic enzyme increased (2,016 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Lacosamide) and Lacosamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.