Lacosamide and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Lacosamide (lacosamide), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Clobazam, and have Status epilepticus.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Lacosamide. It is created by eHealthMe based on reports of 16,542 people who have side effects when taking Lacosamide from the FDA, and is updated regularly.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,954 drugs and 2,940 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

16,542 people reported to have side effects when taking Lacosamide.
Among them, 14 people (0.08%) have Hyperkalemia.

Among these 14 people:

How long have people been on Lacosamide when they have Hyperkalemia? *

What is the gender of people who have Hyperkalemia when taking Lacosamide? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Hyperkalemia when taking Lacosamide? *

What are other drugs people take besides Lacosamide? *

What are other side effects people have besides Hyperkalemia? *

Acidosis (build-up of carbon dioxide in the blood): 3 people, 21.43%
Fatigue (feeling of tiredness): 3 people, 21.43%
Urine Output Decreased: 2 people, 14.29%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 14.29%
Diarrhea: 2 people, 14.29%
Pneumonia: 2 people, 14.29%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 2 people, 14.29%
Drowsiness: 2 people, 14.29%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 14.29%
Drug Ineffective: 2 people, 14.29%

What are the existing conditions these people have? *

Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 3 people, 21.43%
Depression: 2 people, 14.29%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 7.14%
Pneumonia: 1 person, 7.14%
Partial Seizures With Secondary Generalisation (partial seizure may spread within the brain, a process known as secondary generalization): 1 person, 7.14%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 7.14%
Hypokalemia (low potassium): 1 person, 7.14%
Culture Wound Positive: 1 person, 7.14%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.14%
Astrocytoma (tumour of the brain that originate in a particular kind of glial-cells): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Lacosamide and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lacosamide:

Lacosamide (16,601 reports)

Hyperkalemia treatments and more:

Hyperkalemia (78,084 reports)

Browse all side effects of Lacosamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Hyperkalemia (1,954 drugs)

Browse all the conditions that are associated with Hyperkalemia:

Hyperkalemia (2,940 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Lacosamide) and Lacosamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.