Lacosamide and Tonic convulsion - a phase IV clinical study of FDA data

Summary:

Tonic convulsion is reported as a side effect among people who take Lacosamide (lacosamide), especially for people who are female, 2-9 old, also take Levetiracetam, and have Partial seizures.

The phase IV clinical study analyzes which people have Tonic convulsion when taking Lacosamide. It is created by eHealthMe based on reports of 16,542 people who have side effects when taking Lacosamide from the FDA, and is updated regularly.

What is Lacosamide?

Lacosamide has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 16,601 Lacosamide users. Check the latest studies of Lacosamide.

What is Tonic convulsion?

Tonic convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it) is found to be associated with 160 drugs and 384 conditions by eHealthMe. Check the latest studies of Tonic convulsion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

16,542 people reported to have side effects when taking Lacosamide.
Among them, 40 people (0.24%) have Tonic convulsion.

Could Lacosamide cause Tonic convulsion?

Among these 40 people:

What is the gender of people who have Tonic convulsion when taking Lacosamide? *

female: 72.22 %
male: 27.78 %

What is the age of people who have Tonic convulsion when taking Lacosamide? *

What are other drugs people take besides Lacosamide? *

What are other side effects people have besides Tonic convulsion? *

Drug Ineffective: 19 people, 47.50%
Drug Level Increased: 12 people, 30.00%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 17.50%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 5 people, 12.50%
Petit Mal Epilepsy (absence seizure): 5 people, 12.50%
Partial Seizures (seizures which affect only a part of the brain at onset): 5 people, 12.50%
Walking Disability: 2 people, 5.00%
Stereotypy (excessive repetition or lack of variation in movements, ideas, or patterns of speech): 2 people, 5.00%
Anger: 2 people, 5.00%
Fall: 2 people, 5.00%

What are the existing conditions these people have? *

Partial Seizures (seizures which affect only a part of the brain at onset): 19 people, 47.50%
Urinary Tract Infection: 9 people, 22.50%
Stress And Anxiety: 9 people, 22.50%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 9 people, 22.50%
Nervousness: 9 people, 22.50%
Ventricular Arrhythmia (problem with the rate or rhythm of the heartbeat): 4 people, 10.00%
Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 4 people, 10.00%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 5.00%
Arrhythmias (irregular heartbeat): 2 people, 5.00%
Type 2 Diabetes: 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Lacosamide and have Tonic convulsion?

- Check whether Tonic convulsion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lacosamide:

Lacosamide (16,601 reports)

Browse all side effects of Lacosamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tonic convulsion:

Tonic convulsion (160 drugs)

Browse all the conditions that are associated with Tonic convulsion:

Tonic convulsion (384 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Lacosamide) and Lacosamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.