Lamivudine and Motormental retardation - a phase IV clinical study of FDA data

Summary:

Motormental retardation is reported as a side effect among people who take Lamivudine (lamivudine; zidovudine; nevirapine), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Darunavir, and have Depressive symptom.

The phase IV clinical study analyzes which people have Motormental retardation when taking Lamivudine. It is created by eHealthMe based on reports of 17,197 people who have side effects when taking Lamivudine from the FDA, and is updated regularly.

What is Lamivudine?

Lamivudine has active ingredients of lamivudine; zidovudine; nevirapine. It is often used in hiv infection. eHealthMe is studying from 17,242 Lamivudine users. Check the latest studies of Lamivudine.

What is Motormental retardation?

Motormental retardation (a slowing-down of thought and a reduction of physical work) is found to be associated with 271 drugs and 749 conditions by eHealthMe. Check the latest studies of Motormental retardation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 19, 2026

17,197 people reported to have side effects when taking Lamivudine.
Among them, 17 people (0.1%) have Motormental retardation.

Could Lamivudine cause Motormental retardation?

Among these 17 people:

How long have people been on Lamivudine when they have Motormental retardation? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Motormental retardation when taking Lamivudine? *

  • female: 20 %
  • male: 80 %

What is the age of people who have Motormental retardation when taking Lamivudine? *

  • 0-1: 14.29 %
  • 2-9: 14.29 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 7.14 %
  • 40-49: 14.29 %
  • 50-59: 50.0 %
  • 60+: 0.0 %

What are other drugs people take besides Lamivudine? *

  1. Darunavir: 6 people, 35.29%
  2. Ritonavir: 5 people, 29.41%
  3. Atazanavir: 4 people, 23.53%
  4. Zidovudine: 4 people, 23.53%
  5. Tenofovir Disoproxil Fumarate: 3 people, 17.65%
  6. Nexium: 2 people, 11.76%
  7. Intelence: 2 people, 11.76%
  8. Escitalopram: 2 people, 11.76%
  9. Lamictal: 2 people, 11.76%
  10. Zolpidem: 2 people, 11.76%

What are other side effects people have besides Motormental retardation? *

  1. Confusional State: 6 people, 35.29%
  2. Cerebellar Syndrome (impaired blood circulation to cerebellum due to lesion in artery): 6 people, 35.29%
  3. Pathogen Resistance: 6 people, 35.29%
  4. Hyperproteinaemia (a metabolic disorder characterized by enhanced plasma proline concentrations and urinary excretion): 6 people, 35.29%
  5. Pleocytosis (increased cell count): 6 people, 35.29%
  6. Viiith Nerve Injury: 4 people, 23.53%
  7. Facial Paralysis (loss of function of face muscle): 4 people, 23.53%
  8. Vth Nerve Injury: 4 people, 23.53%
  9. Drowsiness: 3 people, 17.65%
  10. Cranial Nerve Palsies Multiple (impaired functioning of multiple cranial nerves): 3 people, 17.65%

What are the existing conditions these people have? *

  1. Stress And Anxiety: 2 people, 11.76%
  2. Depressive Symptom: 2 people, 11.76%
  3. Pulmonary Tuberculosis (lungs tuberculosis): 1 person, 5.88%
  4. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 5.88%
  5. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 5.88%
  6. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 5.88%
  7. Bacterial Infection: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Lamivudine and have Motormental retardation?

- Check whether Motormental retardation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lamivudine:

Motormental retardation treatments and more:

How severe was Motormental retardation and when was it recovered:

Expand to all the drugs that have ingredients of lamivudine; zidovudine; nevirapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamivudine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Motormental retardation:

Browse all the conditions that are associated with Motormental retardation:


How the study uses the data?

The study uses data from the FDA. It is based on lamivudine; zidovudine; nevirapine (the active ingredients of Lamivudine) and Lamivudine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: