Lamotrigine and Borderline personality disorder - a phase IV clinical study of FDA data

Summary:

Borderline personality disorder is reported as a side effect among people who take Lamotrigine (lamotrigine), especially for people who are female, 30-39 old, have been taking the drug for 6 - 12 months also take Xyrem, and have Depression.

The phase IV clinical study analyzes which people have Borderline personality disorder when taking Lamotrigine. It is created by eHealthMe based on reports of 72,834 people who have side effects when taking Lamotrigine from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Borderline personality disorder?

Borderline personality disorder is found to be associated with 175 drugs and 273 conditions by eHealthMe. Check the latest studies of Borderline personality disorder.

On Jul, 19, 2026

72,834 people reported to have side effects when taking Lamotrigine.
Among them, 47 people (0.06%) have Borderline personality disorder.

Could Lamotrigine cause Borderline personality disorder?

Among these 47 people:

How long have people been on Lamotrigine when they have Borderline personality disorder? *

What is the gender of people who have Borderline personality disorder when taking Lamotrigine? *

female: 62.22 %
male: 37.78 %

What is the age of people who have Borderline personality disorder when taking Lamotrigine? *

What are other drugs people take besides Lamotrigine? *

What are other side effects people have besides Borderline personality disorder? *

Drug Ineffective: 17 people, 36.17%
Depression: 16 people, 34.04%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 15 people, 31.91%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 15 people, 31.91%
Suicide Attempt: 14 people, 29.79%
Insomnia (sleeplessness): 12 people, 25.53%
Headache (pain in head): 12 people, 25.53%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 11 people, 23.40%
Diarrhea: 10 people, 21.28%
Emotional Disorder: 10 people, 21.28%

What are the existing conditions these people have? *

Depression: 13 people, 27.66%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 23.40%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 9 people, 19.15%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 14.89%
Stress And Anxiety: 6 people, 12.77%
Sleep Disorder: 5 people, 10.64%
High Blood Pressure: 5 people, 10.64%
Post-Traumatic Stress Disorder: 4 people, 8.51%
Oedema Peripheral (superficial swelling): 4 people, 8.51%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

Do you take Lamotrigine and have Borderline personality disorder?

- Check whether Borderline personality disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lamotrigine:

Lamotrigine (76,638 reports)

Browse all side effects of Lamotrigine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Borderline personality disorder:

Borderline personality disorder (175 drugs)

Browse all the conditions that are associated with Borderline personality disorder:

Borderline personality disorder (273 conditions)

Related publications that referenced our studies

Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.