Lamotrigine and Hypoaesthesia oral - a phase IV clinical study of FDA data

Summary:

Hypoaesthesia oral is reported as a side effect among people who take Lamotrigine (lamotrigine), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Melatonin, and have Affective disorder.

The phase IV clinical study analyzes which people have Hypoaesthesia oral when taking Lamotrigine. It is created by eHealthMe based on reports of 72,834 people who have side effects when taking Lamotrigine from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Hypoaesthesia oral?

Hypoaesthesia oral (reduced sense of touch or sensation in mouth) is found to be associated with 1,089 drugs and 1,013 conditions by eHealthMe. Check the latest studies of Hypoaesthesia oral.

On Jul, 15, 2026

72,834 people reported to have side effects when taking Lamotrigine.
Among them, 75 people (0.1%) have Hypoaesthesia oral.

Could Lamotrigine cause Hypoaesthesia oral?

Among these 75 people:

How long have people been on Lamotrigine when they have Hypoaesthesia oral? *

What is the gender of people who have Hypoaesthesia oral when taking Lamotrigine? *

female: 84.62 %
male: 15.38 %

What is the age of people who have Hypoaesthesia oral when taking Lamotrigine? *

What are other drugs people take besides Lamotrigine? *

What are other side effects people have besides Hypoaesthesia oral? *

Dizziness: 27 people, 36.00%
Hypoaesthesia (reduced sense of touch or sensation): 23 people, 30.67%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 20 people, 26.67%
Dyspnea (difficult or laboured breathing): 16 people, 21.33%
Malaise (a feeling of general discomfort or uneasiness): 14 people, 18.67%
Nausea (feeling of having an urge to vomit): 13 people, 17.33%
Agitation (state of anxiety or nervous excitement): 12 people, 16.00%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 11 people, 14.67%
Abdominal Discomfort: 10 people, 13.33%
Taste - Impaired: 10 people, 13.33%

What are the existing conditions these people have? *

Affective Disorder (mental disorder): 14 people, 18.67%
Drowsiness: 6 people, 8.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 6.67%
Depression: 5 people, 6.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 6.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 5.33%
Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 4 people, 5.33%
Abdominal Discomfort: 4 people, 5.33%
Pain In Extremity: 3 people, 4.00%
Nausea (feeling of having an urge to vomit): 3 people, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lamotrigine and have Hypoaesthesia oral?

- Check whether Hypoaesthesia oral is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lamotrigine:

Lamotrigine (76,638 reports)

Browse all side effects of Lamotrigine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoaesthesia oral:

Hypoaesthesia oral (1,089 drugs)

Browse all the conditions that are associated with Hypoaesthesia oral:

Hypoaesthesia oral (1,013 conditions)

Related publications that referenced our studies

Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.