Lamotrigine and Hypocalcaemia - a phase IV clinical study of FDA data

Summary:

Hypocalcaemia is reported as a side effect among people who take Lamotrigine (lamotrigine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vimpat, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Hypocalcaemia when taking Lamotrigine. It is created by eHealthMe based on reports of 72,834 people who have side effects when taking Lamotrigine from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Hypocalcaemia?

Hypocalcaemia (levels of calcium in blood serum are abnormally low) is found to be associated with 1,207 drugs and 1,302 conditions by eHealthMe. Check the latest studies of Hypocalcaemia.

On Jul, 05, 2026

72,834 people reported to have side effects when taking Lamotrigine.
Among them, 73 people (0.1%) have Hypocalcaemia.

Among these 73 people:

How long have people been on Lamotrigine when they have Hypocalcaemia? *

What is the gender of people who have Hypocalcaemia when taking Lamotrigine? *

female: 36.92 %
male: 63.08 %

What is the age of people who have Hypocalcaemia when taking Lamotrigine? *

What are other drugs people take besides Lamotrigine? *

What are other side effects people have besides Hypocalcaemia? *

Rickets (softening of bones): 34 people, 46.58%
Hypokalemia (low potassium): 14 people, 19.18%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 9 people, 12.33%
Suicide Attempt: 8 people, 10.96%
Electrocardiogram Qt Prolonged: 8 people, 10.96%
Drug Ineffective: 8 people, 10.96%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 6 people, 8.22%
Dizziness: 5 people, 6.85%
Hypernatraemia (an abnormally high plasma concentration of sodium ions): 5 people, 6.85%
Thrombocytopenia (decrease of platelets in blood): 4 people, 5.48%

What are the existing conditions these people have? *

Parkinson's Disease: 20 people, 27.40%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 10.96%
Brain Neoplasm (tumour of brain): 8 people, 10.96%
Gastric Ulcer (stomach ulcer): 7 people, 9.59%
Suicide Attempt: 4 people, 5.48%
Rickets (softening of bones): 3 people, 4.11%
Respiratory Tract Infection: 3 people, 4.11%
Breast Cancer Metastatic: 2 people, 2.74%
Depression: 2 people, 2.74%
Conversion Disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause): 2 people, 2.74%

* Approximation only. Some reports may have incomplete information.

Do you take Lamotrigine and have Hypocalcaemia?

- Check whether Hypocalcaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lamotrigine:

Lamotrigine (76,638 reports)

Hypocalcaemia treatments and more:

Hypocalcaemia (26,346 reports)

Browse all side effects of Lamotrigine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypocalcaemia:

Hypocalcaemia (1,207 drugs)

Browse all the conditions that are associated with Hypocalcaemia:

Hypocalcaemia (1,302 conditions)

Related publications that referenced our studies

Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.