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Lamotrigine and Myositis - a phase IV clinical study of FDA data

Summary:

Myositis is reported as a side effect among people who take Lamotrigine (lamotrigine), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Brintellix, and have Borderline personality disorder.

The phase IV clinical study analyzes which people have Myositis when taking Lamotrigine. It is created by eHealthMe based on reports of 72,834 people who have side effects when taking Lamotrigine from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Myositis?

Myositis (inflammation of the muscles) is found to be associated with 827 drugs and 1,135 conditions by eHealthMe. Check the latest studies of Myositis.

On Jul, 10, 2026

72,834 people reported to have side effects when taking Lamotrigine.
Among them, 21 people (0.03%) have Myositis.

Could Lamotrigine cause Myositis?

Among these 21 people:

How long have people been on Lamotrigine when they have Myositis? *

  • < 1 month: 83.33 %
  • 1 - 6 months: 16.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Myositis when taking Lamotrigine? *

  • female: 70.59 %
  • male: 29.41 %

What is the age of people who have Myositis when taking Lamotrigine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 5.88 %
  • 20-29: 47.06 %
  • 30-39: 5.88 %
  • 40-49: 23.53 %
  • 50-59: 0.0 %
  • 60+: 17.65 %

What are other drugs people take besides Lamotrigine? *

  1. Brintellix: 5 people, 23.81%
  2. Vimpat: 3 people, 14.29%
  3. Clopidogrel: 2 people, 9.52%
  4. Keytruda: 2 people, 9.52%
  5. Escitalopram: 2 people, 9.52%
  6. Latuda: 2 people, 9.52%
  7. Amitriptyline Hydrochloride: 1 person, 4.76%
  8. Atenolol: 1 person, 4.76%
  9. Avonex: 1 person, 4.76%
  10. Aloe Vera: 1 person, 4.76%

What are other side effects people have besides Myositis? *

  1. Eosinophilia (eosinophil count in the peripheral blood exceeds): 6 people, 28.57%
  2. Muscle Aches (muscle pain): 4 people, 19.05%
  3. Muscle Spasms (muscle contraction): 4 people, 19.05%
  4. Hyperthyroidism (over activity of the thyroid gland): 3 people, 14.29%
  5. Thyroiditis (inflammation of thyroid gland): 3 people, 14.29%
  6. Fasciitis (infection of muscle surrounding tissue): 3 people, 14.29%
  7. Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 3 people, 14.29%
  8. Peripheral Nerve Paresis: 3 people, 14.29%
  9. Myopathy (a muscular disease in which the muscle fibres do not function): 3 people, 14.29%
  10. Weakness: 2 people, 9.52%

What are the existing conditions these people have? *

  1. Borderline Personality Disorder: 5 people, 23.81%
  2. Pain: 2 people, 9.52%
  3. Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 2 people, 9.52%
  4. Hypercoagulation (increased tendency for clotting of the blood): 2 people, 9.52%
  5. Bladder Cancer: 2 people, 9.52%
  6. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 4.76%
  7. Stress And Anxiety: 1 person, 4.76%
  8. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 4.76%
  9. Pemphigoid (tense blisters on the skin): 1 person, 4.76%
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Lamotrigine and have Myositis?

- Check whether Myositis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lamotrigine:

Myositis treatments and more:

How severe was Myositis and when was it recovered:

Expand to all the drugs that have ingredients of lamotrigine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamotrigine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myositis:

Browse all the conditions that are associated with Myositis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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