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Lamotrigine and Poor peripheral circulation - a phase IV clinical study of FDA data

Summary:

Poor peripheral circulation is reported as a side effect among people who take Lamotrigine (lamotrigine), especially for people who are female, 50-59 old, also take Gabapentin, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Poor peripheral circulation when taking Lamotrigine. It is created by eHealthMe based on reports of 72,834 people who have side effects when taking Lamotrigine from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,639 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Poor peripheral circulation?

Poor peripheral circulation is found to be associated with 532 drugs and 695 conditions by eHealthMe. Check the latest studies of Poor peripheral circulation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

72,834 people reported to have side effects when taking Lamotrigine.
Among them, 16 people (0.02%) have Poor peripheral circulation.

Could Lamotrigine cause Poor peripheral circulation?

Among these 16 people:

What is the gender of people who have Poor peripheral circulation when taking Lamotrigine? *

  • female: 53.85 %
  • male: 46.15 %

What is the age of people who have Poor peripheral circulation when taking Lamotrigine? *

  • 0-1: 0.0 %
  • 2-9: 7.69 %
  • 10-19: 7.69 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 15.38 %
  • 50-59: 53.85 %
  • 60+: 15.38 %

What are other drugs people take besides Lamotrigine? *

  1. Gabapentin: 5 people, 31.25%
  2. Amoxicillin: 4 people, 25.00%
  3. Testosterone: 3 people, 18.75%
  4. Atorvastatin Calcium: 3 people, 18.75%
  5. Lithium Carbonate: 3 people, 18.75%
  6. Clonazepam: 3 people, 18.75%
  7. Lyrica: 3 people, 18.75%
  8. Baclofen: 3 people, 18.75%
  9. Vumerity: 3 people, 18.75%
  10. Metformin Hydrochloride: 3 people, 18.75%

What are other side effects people have besides Poor peripheral circulation? *

  1. Joint Pain: 9 people, 56.25%
  2. Tinnitus (a ringing in the ears): 9 people, 56.25%
  3. Weight Increased: 8 people, 50.00%
  4. Depression: 8 people, 50.00%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 43.75%
  6. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 6 people, 37.50%
  7. Muscle Spasms (muscle contraction): 6 people, 37.50%
  8. Eye Inflammation: 6 people, 37.50%
  9. Photosensitivity Reaction: 6 people, 37.50%
  10. Generalised Oedema (swelling all over the body): 6 people, 37.50%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 18.75%
  2. Thyroid Diseases: 1 person, 6.25%
  3. Stress And Anxiety: 1 person, 6.25%
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 6.25%
  5. Pain: 1 person, 6.25%
  6. Osteoporosis (bones weak and more likely to break): 1 person, 6.25%
  7. Insomnia (sleeplessness): 1 person, 6.25%
  8. Indigestion: 1 person, 6.25%
  9. Hypersensitivity: 1 person, 6.25%
  10. High Blood Pressure: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lamotrigine and have Poor peripheral circulation?

- Check whether Poor peripheral circulation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lamotrigine:

Poor peripheral circulation treatments and more:

How severe was Poor peripheral circulation and when was it recovered:

Expand to all the drugs that have ingredients of lamotrigine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamotrigine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Poor peripheral circulation:

Browse all the conditions that are associated with Poor peripheral circulation:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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