Lamotrigine and Seizures - a phase IV clinical study of FDA data
Summary:
Seizures is found among people who take Lamotrigine, especially for people who are female, 20-29 old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Lamotrigine and have Seizures. It is created by eHealthMe based on reports of 61,601 people who have side effects when taking Lamotrigine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
61,601 people reported to have side effects when taking Lamotrigine.
Among them, 3,463 people (5.62%) have Seizures.
What is Lamotrigine?
Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 65,137 Lamotrigine users for its effectiveness, alternative drugs and more.
What is Seizures?
Seizures (abnormal excessive or synchronous neuronal activity in the brain) is found to be associated with 2,866 drugs and 2,141 conditions by eHealthMe.
Number of Lamotrigine and Seizures reports submitted per year:

Time on Lamotrigine when people have Seizures *:
Gender of people who have Seizures when taking Lamotrigine*:
Age of people who have Seizures when taking Lamotrigine *:
Common drugs people take besides Lamotrigine *:
Common side effects people have besides Seizures *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Lamotrigine and have Seizures?
Check whether Seizures is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
Related studies
How severe was Seizures and when was it recovered:
Expand to all the drugs that have ingredients of lamotrigine:
- Seizures and drugs with ingredients of lamotrigine (5,747 reports)
Alternative drugs to, pros and cons of Lamotrigine:
- Lamotrigine (65,137 reports)
Common Lamotrigine side effects:
- Drug ineffective: 4,944 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3,463 reports
- Rashes (redness): 3,102 reports
- Dizziness: 2,881 reports
- Fatigue (feeling of tiredness): 2,878 reports
- Headache (pain in head): 2,487 reports
Browse all side effects of Lamotrigine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSeizures treatments and more:
- Seizures (122,961 reports)
COVID vaccines that are related to Seizures:
- Seizures in Moderna COVID Vaccine
- Seizures in Pfizer BioNTech Covid Vaccine
- Seizures in Johnson and Johnson Covid Vaccine
Common drugs associated with Seizures:
- Levetiracetam: 7,432 reports
- Keppra: 6,563 reports
- Epidiolex: 4,121 reports
- Lamotrigine: 3,463 reports
- Vimpat: 3,176 reports
- Lamictal: 2,547 reports
- Gabapentin: 2,503 reports
- Lacosamide: 2,437 reports
- Clonazepam: 2,405 reports
- Humira: 2,379 reports
All the drugs that are associated with Seizures:
- Seizures (2,866 drugs)
Common conditions associated with Seizures:
- Epilepsy: 9,254 reports
- Multiple sclerosis: 6,059 reports
- Depression: 2,604 reports
- Pain: 2,466 reports
- High blood pressure: 1,990 reports
All the conditions that are associated with Seizures:
- Seizures (2,141 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on lamotrigine (the active ingredients of Lamotrigine) and Lamotrigine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Azacitidine and Ataxia Aggravated - 3 seconds ago
- Otrexup and Blood Pressure Management - 5 seconds ago
- Eplerenone and Dobutrex drug interaction - 15 seconds ago
- Zithromax and Aspirin drug interaction - 18 seconds ago
- Tamsulosin and Ecchymosis - 20 seconds ago
- Combipatch and Lipitor drug interaction - 49 seconds ago
- Chromic Chloride and Vomiting Aggravated - 49 seconds ago
- Sertraline and Hypoglycaemic Unconsciousness - a minute ago
- Phenytoin Sodium and Panic Reaction Aggravated - a minute ago
- Pegasys vs. Ribasphere - a minute ago