Lanoxin and Orthostatic hypotension - a phase IV clinical study of FDA data

Summary:

Orthostatic hypotension is reported as a side effect among people who take Lanoxin (digoxin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have High blood pressure.

The phase IV clinical study analyzes which people have Orthostatic hypotension when taking Lanoxin. It is created by eHealthMe based on reports of 21,602 people who have side effects when taking Lanoxin from the FDA, and is updated regularly.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

What is Orthostatic hypotension?

Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up) is found to be associated with 1,234 drugs and 1,336 conditions by eHealthMe. Check the latest studies of Orthostatic hypotension.



On Jul, 17, 2026

21,602 people reported to have side effects when taking Lanoxin.
Among them, 83 people (0.38%) have Orthostatic hypotension.

Could Lanoxin cause Orthostatic hypotension?

Among these 83 people:

How long have people been on Lanoxin when they have Orthostatic hypotension? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Orthostatic hypotension when taking Lanoxin? *

  • female: 37.18 %
  • male: 62.82 %

What is the age of people who have Orthostatic hypotension when taking Lanoxin? *

  • 0-1: 2.82 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 1.41 %
  • 50-59: 5.63 %
  • 60+: 90.14 %

What are other drugs people take besides Lanoxin? *

  1. Lasix: 28 people, 33.73%
  2. Coumadin: 17 people, 20.48%
  3. Furosemide: 17 people, 20.48%
  4. Coreg: 16 people, 19.28%
  5. Altace: 14 people, 16.87%
  6. Protonix: 13 people, 15.66%
  7. Norvasc: 13 people, 15.66%
  8. Flomax: 12 people, 14.46%
  9. Aspirin: 11 people, 13.25%
  10. Augmentin '125': 11 people, 13.25%

What are other side effects people have besides Orthostatic hypotension? *

  1. Fainting (loss of consciousness and postural tone): 29 people, 34.94%
  2. Fall: 18 people, 21.69%
  3. Dizziness: 17 people, 20.48%
  4. Dyspnea (difficult or laboured breathing): 16 people, 19.28%
  5. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 15 people, 18.07%
  6. Weakness: 15 people, 18.07%
  7. Fatigue (feeling of tiredness): 15 people, 18.07%
  8. Anaemia (lack of blood): 14 people, 16.87%
  9. Chest Pain: 14 people, 16.87%
  10. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 13 people, 15.66%

What are the existing conditions these people have? *

  1. High Blood Pressure: 13 people, 15.66%
  2. Enlarged Prostate: 9 people, 10.84%
  3. Cardiac Failure: 8 people, 9.64%
  4. Cardiac Failure Congestive: 8 people, 9.64%
  5. Parkinson's Disease: 6 people, 7.23%
  6. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 6.02%
  7. Arrhythmias (irregular heartbeat): 5 people, 6.02%
  8. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 5 people, 6.02%
  9. Hallucinations (sensations that appear real but are created by your mind): 4 people, 4.82%
  10. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 4.82%

* Approximation only. Some reports may have incomplete information.

Do you take Lanoxin and have Orthostatic hypotension?

- Check whether Orthostatic hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lanoxin:

Orthostatic hypotension treatments and more:

How severe was Orthostatic hypotension and when was it recovered:

Expand to all the drugs that have ingredients of digoxin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Orthostatic hypotension:

Browse all the conditions that are associated with Orthostatic hypotension:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on digoxin (the active ingredients of Lanoxin) and Lanoxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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