Leflunomide and Hypogeusia - a phase IV clinical study of FDA data

Summary:

Hypogeusia is reported as a side effect among people who take Leflunomide (leflunomide), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Cosentyx, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Hypogeusia when taking Leflunomide. It is created by eHealthMe based on reports of 81,713 people who have side effects when taking Leflunomide from the FDA, and is updated regularly.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

What is Hypogeusia?

Hypogeusia (reduced ability to taste things (to taste sweet, sour, bitter, or salty substances)) is found to be associated with 270 drugs and 387 conditions by eHealthMe. Check the latest studies of Hypogeusia.

On Jul, 17, 2026

81,713 people reported to have side effects when taking Leflunomide.
Among them, 30 people (0.04%) have Hypogeusia.

Among these 30 people:

How long have people been on Leflunomide when they have Hypogeusia? *

What is the gender of people who have Hypogeusia when taking Leflunomide? *

female: 67.86 %
male: 32.14 %

What is the age of people who have Hypogeusia when taking Leflunomide? *

What are other drugs people take besides Leflunomide? *

What are other side effects people have besides Hypogeusia? *

Dyspnea (difficult or laboured breathing): 18 people, 60.00%
Oropharyngeal Pain: 18 people, 60.00%
Dry Mouth: 18 people, 60.00%
Peripheral Swelling: 16 people, 53.33%
Nasopharyngitis (inflammation of the nasopharynx): 14 people, 46.67%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 14 people, 46.67%
Fatigue (feeling of tiredness): 14 people, 46.67%
Muscle Aches (muscle pain): 13 people, 43.33%
Joint Pain: 13 people, 43.33%
Back Pain: 12 people, 40.00%

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 18 people, 60.00%
Pain In Extremity: 5 people, 16.67%
Pain: 5 people, 16.67%
Muscle Spasms (muscle contraction): 5 people, 16.67%
High Blood Cholesterol: 5 people, 16.67%
Myositis (inflammation of the muscles): 3 people, 10.00%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Leflunomide and have Hypogeusia?

- Check whether Hypogeusia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Leflunomide:

Leflunomide (82,105 reports)

Hypogeusia treatments and more:

Hypogeusia (2,199 reports)

Browse all side effects of Leflunomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypogeusia:

Hypogeusia (270 drugs)

Browse all the conditions that are associated with Hypogeusia:

Hypogeusia (387 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Leflunomide) and Leflunomide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.