Leflunomide and Muscle spasms - a phase IV clinical study of FDA data

Summary:

Muscle spasms is reported as a side effect among people who take Leflunomide (leflunomide), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Enbrel, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Muscle spasms when taking Leflunomide. It is created by eHealthMe based on reports of 81,713 people who have side effects when taking Leflunomide from the FDA, and is updated regularly.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

What is Muscle spasms?

Muscle spasms (muscle contraction) is found to be associated with 2,664 drugs and 3,101 conditions by eHealthMe. Check the latest studies of Muscle spasms.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

81,713 people reported to have side effects when taking Leflunomide.
Among them, 1,290 people (1.58%) have Muscle spasms.

Among these 1,290 people:

* Approximation only. Some reports may have incomplete information.

Do you take Leflunomide and have Muscle spasms?

- Check whether Muscle spasms is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Leflunomide:

Leflunomide (82,105 reports)

Muscle spasms treatments and more:

Muscle spasms (238,423 reports)

How severe was Muscle spasms and when was it recovered:

Muscle spasms in Leflunomide

Expand to all the drugs that have ingredients of leflunomide:

Muscle spasms and drugs with ingredients of leflunomide (1,878 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Leflunomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle spasms:

Muscle spasms (2,664 drugs)

Browse all the conditions that are associated with Muscle spasms:

Muscle spasms (3,101 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Leflunomide) and Leflunomide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.