Letairis and Aspiration pleural cavity abnormal - a phase IV clinical study of FDA data

Summary:

Aspiration pleural cavity abnormal is reported as a side effect among people who take Letairis (ambrisentan), especially for people who are female, 60+ old, also take Adcirca, and have Systemic sclerosis (scleroderma).

The phase IV clinical study analyzes which people have Aspiration pleural cavity abnormal when taking Letairis. It is created by eHealthMe based on reports of 93,991 people who have side effects when taking Letairis from the FDA, and is updated regularly.

What is Letairis?

Letairis has active ingredients of ambrisentan. It is often used in pulmonary hypertension. eHealthMe is studying from 94,041 Letairis users. Check the latest studies of Letairis.

What is Aspiration pleural cavity abnormal?

Aspiration pleural cavity abnormal is found to be associated with 324 drugs and 174 conditions by eHealthMe. Check the latest studies of Aspiration pleural cavity abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

93,991 people reported to have side effects when taking Letairis.
Among them, 39 people (0.04%) have Aspiration pleural cavity abnormal.

Could Letairis cause Aspiration pleural cavity abnormal?

Among these 39 people:

What is the gender of people who have Aspiration pleural cavity abnormal when taking Letairis? *

female: 76.92 %
male: 23.08 %

What is the age of people who have Aspiration pleural cavity abnormal when taking Letairis? *

What are other drugs people take besides Letairis? *

What are other side effects people have besides Aspiration pleural cavity abnormal? *

Dyspnea (difficult or laboured breathing): 19 people, 48.72%
Pleural Effusion (water on the lungs): 16 people, 41.03%
Fluid Retention (an abnormal accumulation of fluid in the blood): 13 people, 33.33%
Nausea (feeling of having an urge to vomit): 12 people, 30.77%
Diarrhea: 11 people, 28.21%
Pulmonary Oedema (fluid accumulation in the lungs): 10 people, 25.64%
Chest Pain: 10 people, 25.64%
Headache (pain in head): 9 people, 23.08%
Lung Disorder (lung disease): 8 people, 20.51%
Oedema (fluid collection in tissue): 7 people, 17.95%

What are the existing conditions these people have? *

Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 3 people, 7.69%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 5.13%
Weight Loss: 1 person, 2.56%
Systemic Sclerosis (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 2.56%
Sleep Apnea Syndrome: 1 person, 2.56%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 2.56%
Cor Pulmonale Chronic (long lasting enlargement of the right ventricle of the heart): 1 person, 2.56%
Connective Tissue Disorder (any disease that has the connective tissues of the body): 1 person, 2.56%
Chronic Renal Failure (kidney failure): 1 person, 2.56%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Letairis and have Aspiration pleural cavity abnormal?

- Check whether Aspiration pleural cavity abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Letairis:

Letairis (94,041 reports)

Browse all side effects of Letairis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aspiration pleural cavity abnormal:

Aspiration pleural cavity abnormal (324 drugs)

Browse all the conditions that are associated with Aspiration pleural cavity abnormal:

Aspiration pleural cavity abnormal (174 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ambrisentan (the active ingredients of Letairis) and Letairis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.