Letrozole and Herniated nucleus pulposus (slipped disk) - a phase IV clinical study of FDA data

Summary:

Herniated nucleus pulposus (slipped disk) is reported as a side effect among people who take Letrozole (letrozole), especially for people who are female, 50-59 old, also take Xeloda, and have Hypercalcaemia.

The phase IV clinical study analyzes which people have Herniated nucleus pulposus (slipped disk) when taking Letrozole. It is created by eHealthMe based on reports of 53,470 people who have side effects when taking Letrozole from the FDA, and is updated regularly.

What is Letrozole?

Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 54,125 Letrozole users. Check the latest studies of Letrozole.

What is Herniated nucleus pulposus (slipped disk)?

Herniated nucleus pulposus (slipped disk) is found to be associated with 583 drugs and 909 conditions by eHealthMe. Check the latest studies of Herniated nucleus pulposus (slipped disk).

On Jul, 05, 2026

53,470 people reported to have side effects when taking Letrozole.
Among them, 39 people (0.07%) have Herniated nucleus pulposus (slipped disk).

Could Letrozole cause Herniated nucleus pulposus (slipped disk)?

Among these 39 people:

What is the gender of people who have Herniated nucleus pulposus (slipped disk) when taking Letrozole? *

female: 97.44 %
male: 2.56 %

What is the age of people who have Herniated nucleus pulposus (slipped disk) when taking Letrozole? *

What are other drugs people take besides Letrozole? *

What are other side effects people have besides Herniated nucleus pulposus (slipped disk)? *

Hypoaesthesia (reduced sense of touch or sensation): 38 people, 97.44%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 36 people, 92.31%
Spinal Osteoarthritis (joint cartilage loss in spine): 36 people, 92.31%
Stress And Anxiety: 36 people, 92.31%
Metastases To Bone (cancer spreads to bone): 36 people, 92.31%
Neuralgia (pain in one or more nerves): 36 people, 92.31%
Impaired Healing: 36 people, 92.31%
Bone Disorder: 36 people, 92.31%
Pain In Extremity: 36 people, 92.31%
Back Pain: 36 people, 92.31%

What are the existing conditions these people have? *

Hypercalcaemia (elevated calcium (ca+) level in the blood): 23 people, 58.97%
Fungal Infection: 11 people, 28.21%
Breast Cancer Female: 2 people, 5.13%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 2.56%
Neuropathy Peripheral (surface nerve damage): 1 person, 2.56%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.56%
Migraine (headache): 1 person, 2.56%
Metastases To Bone (cancer spreads to bone): 1 person, 2.56%
Memory Loss: 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Letrozole and have Herniated nucleus pulposus (slipped disk)?

- Check whether Herniated nucleus pulposus (slipped disk) is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Letrozole:

Letrozole (54,125 reports)

Herniated nucleus pulposus (slipped disk) treatments and more:

Herniated nucleus pulposus (slipped disk) (5,608 reports)

How severe was Herniated nucleus pulposus (slipped disk) and when was it recovered:

Herniated nucleus pulposus (slipped disk) in Letrozole

Expand to all the drugs that have ingredients of letrozole:

Herniated nucleus pulposus (slipped disk) and drugs with ingredients of letrozole (73 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Letrozole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herniated nucleus pulposus (slipped disk):

Herniated nucleus pulposus (slipped disk) (583 drugs)

Browse all the conditions that are associated with Herniated nucleus pulposus (slipped disk):

Herniated nucleus pulposus (slipped disk) (909 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on letrozole (the active ingredients of Letrozole) and Letrozole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.