Letrozole and Monocyte count decreased - a phase IV clinical study of FDA data

Summary:

Monocyte count decreased is reported as a side effect among people who take Letrozole (letrozole), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Kisqali, and have Metastases to bone.

The phase IV clinical study analyzes which people have Monocyte count decreased when taking Letrozole. It is created by eHealthMe based on reports of 53,470 people who have side effects when taking Letrozole from the FDA, and is updated regularly.

What is Letrozole?

Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 54,125 Letrozole users. Check the latest studies of Letrozole.

What is Monocyte count decreased?

Monocyte count decreased is found to be associated with 312 drugs and 393 conditions by eHealthMe. Check the latest studies of Monocyte count decreased.



On Jul, 11, 2026

53,470 people reported to have side effects when taking Letrozole.
Among them, 83 people (0.16%) have Monocyte count decreased.

Could Letrozole cause Monocyte count decreased?

Among these 83 people:

How long have people been on Letrozole when they have Monocyte count decreased? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Monocyte count decreased when taking Letrozole? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Monocyte count decreased when taking Letrozole? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10.0 %
  • 50-59: 8.75 %
  • 60+: 81.25 %

What are other drugs people take besides Letrozole? *

  1. Kisqali: 30 people, 36.14%
  2. Zoledronic Acid: 24 people, 28.92%
  3. Ibrance: 24 people, 28.92%
  4. Palbociclib: 23 people, 27.71%
  5. Senna: 11 people, 13.25%
  6. Senna Alexandrina: 11 people, 13.25%
  7. Zometa: 8 people, 9.64%
  8. Aspirin: 6 people, 7.23%
  9. Femara: 5 people, 6.02%
  10. Levothyroxine Sodium: 5 people, 6.02%

What are other side effects people have besides Monocyte count decreased? *

  1. White Blood Cell Count Decreased: 66 people, 79.52%
  2. Haemoglobin Decreased: 66 people, 79.52%
  3. Haematocrit Decreased: 60 people, 72.29%
  4. Thrombocytopenia (decrease of platelets in blood): 57 people, 68.67%
  5. Lymphocyte Count Decreased: 53 people, 63.86%
  6. Fatigue (feeling of tiredness): 38 people, 45.78%
  7. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 38 people, 45.78%
  8. Fever: 36 people, 43.37%
  9. Red Blood Cell Count Decreased: 34 people, 40.96%
  10. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 34 people, 40.96%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 24 people, 28.92%
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 23 people, 27.71%
  3. Dyspnea (difficult or laboured breathing): 14 people, 16.87%
  4. Constipation: 7 people, 8.43%
  5. Osteoporosis (bones weak and more likely to break): 7 people, 8.43%
  6. High Blood Pressure: 5 people, 6.02%
  7. Arrhythmias (irregular heartbeat): 4 people, 4.82%
  8. Stress And Anxiety: 4 people, 4.82%
  9. Pain: 4 people, 4.82%
  10. Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 3 people, 3.61%

* Approximation only. Some reports may have incomplete information.

Do you take Letrozole and have Monocyte count decreased?

- Check whether Monocyte count decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Letrozole:

Monocyte count decreased treatments and more:

How severe was Monocyte count decreased and when was it recovered:

Expand to all the drugs that have ingredients of letrozole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Letrozole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Monocyte count decreased:

Browse all the conditions that are associated with Monocyte count decreased:


How the study uses the data?

The study uses data from the FDA. It is based on letrozole (the active ingredients of Letrozole) and Letrozole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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