Leukine and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Leukine (sargramostim), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Nexium, and have Malignant melanoma.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Leukine. It is created by eHealthMe based on reports of 2,173 people who have side effects when taking Leukine from the FDA, and is updated regularly.

What is Leukine?

Leukine has active ingredients of sargramostim. eHealthMe is studying from 2,188 Leukine users. Check the latest studies of Leukine.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,954 drugs and 2,940 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 07, 2026

2,173 people reported to have side effects when taking Leukine.
Among them, 11 people (0.51%) have Hyperkalemia.

Among these 11 people:

How long have people been on Leukine when they have Hyperkalemia? *

What is the gender of people who have Hyperkalemia when taking Leukine? *

female: 50 %
male: 50 %

What is the age of people who have Hyperkalemia when taking Leukine? *

What are other drugs people take besides Leukine? *

What are other side effects people have besides Hyperkalemia? *

Anaemia (lack of blood): 7 people, 63.64%
Fever: 7 people, 63.64%
Weight Decreased: 6 people, 54.55%
Hypokalemia (low potassium): 6 people, 54.55%
Acute Kidney Failure: 6 people, 54.55%
Colitis (inflammation of colon): 6 people, 54.55%
Diarrhea: 6 people, 54.55%
Fainting (loss of consciousness and postural tone): 6 people, 54.55%
Intestinal Obstruction: 4 people, 36.36%
Constipation: 4 people, 36.36%

What are the existing conditions these people have? *

Malignant Melanoma (skin cancer rises from melancytes): 8 people, 72.73%
Malignant Melanoma Stage Iv (the cancer has spread to other places in the body, such as the lung, liver, brain, bone, soft tissue, or gastrointestinal (gi) tract. cancer may have spread to places in the skin far away from where it first started): 2 people, 18.18%
Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 1 person, 9.09%
Pain: 1 person, 9.09%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 1 person, 9.09%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Leukine and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Leukine:

Leukine (2,188 reports)

Hyperkalemia treatments and more:

Hyperkalemia (78,084 reports)

Browse all side effects of Leukine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Hyperkalemia (1,954 drugs)

Browse all the conditions that are associated with Hyperkalemia:

Hyperkalemia (2,940 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sargramostim (the active ingredients of Leukine) and Leukine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.